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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Williams, Ebonee Regisford, Gloria Neelgund, Gururaj M. Oyefusi, Adebola Olanipekun, Opeyemi Peterson, Deforest Carson, Laura Stone, Julia M. Oki, Aderemi |
| Description | Country affiliation: United States Author Affiliation: Oyefusi A ( Department of Chemistry, Prairie View A&M University, Prairie View, TX 77446, United States.); Olanipekun O ( Department of Chemistry, Prairie View A&M University, Prairie View, TX 77446, United States.); Neelgund GM ( Department of Chemistry, Prairie View A&M University, Prairie View, TX 77446, United States.); Peterson D ( Cooperative Agricultural Research Center, Prairie View A&M University, Prairie View, TX 77446, United States.); Stone JM ( Cooperative Agricultural Research Center, Prairie View A&M University, Prairie View, TX 77446, United States.); Williams E ( Cooperative Agricultural Research Center, Prairie View A&M University, Prairie View, TX 77446, United States.); Carson L ( Cooperative Agricultural Research Center, Prairie View A&M University, Prairie View, TX 77446, United States.); Regisford G ( Department of Biology, Prairie View A&M University, Prairie View, TX 77446, United States.); Oki A ( Department of Chemistry, Prairie View A&M University, Prairie View, TX 77446, United States. Electronic address: aroki@pvamu.edu.) |
| Abstract | In the present study, hydroxyapatite (HA) was successfully grafted to carboxylated carbon nanotubes (CNTs) and graphene nanosheets. The HA grafted CNTs and HA-graphene nanosheets were characterized using FT-IR, TGA, SEM and X-ray diffraction. The HA grafted CNTs and graphene nanosheets (CNTs-HA and Gr-HA) were further used to examine the proliferation and differentiation rate of temperature-sensitive human fetal osteoblastic cell line (hFOB 1.19). Total protein assays and western blot analysis of osteocalcin expression were used as indicators of cell proliferation and differentiation. Results indicated that hFOB 1.19 cells proliferate and differentiate well in treatment media containing CNTs-HA and graphene-HA. Both CNTs-HA and graphene-HA could be promising nanomaterials for use as scaffolds in bone tissue engineering. |
| ISSN | 13861425 |
| e-ISSN | 18733557 |
| DOI | 10.1016/j.saa.2014.04.004 |
| Journal | Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy |
| Volume Number | 132 |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2014-11-11 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | Open |
| Subject Keyword | Bone And Bones Physiology Durapatite Chemistry Graphite Nanoparticles Nanotubes, Carbon Prostheses And Implants Blotting, Western Cell Line Fetus Cytology Ultrastructure Osteoblasts Osteocalcin Metabolism Spectroscopy, Fourier Transform Infrared Temperature Thermogravimetry X-ray Diffraction Research Support, N.i.h., Extramural Research Support, Non-u.s. Gov't Discipline Spectroscopy |
| Content Type | Text |
| Resource Type | Article |
| Subject | Spectroscopy Atomic and Molecular Physics, and Optics Analytical Chemistry Instrumentation |
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