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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Fujishima, Hiroshi Kamei, Yuko Goto, Mari Yamagami, Satoru Ichinose, Takamichi Mimura, Tatsuya Takada, Sachiko Matsubara, Masao |
| Spatial Coverage | Japan |
| Description | Author Affiliation: Mimura T ( Department of Ophthalmology, Tokyo Women's Medical University Medical Center East, Tokyo, Japan); Ichinose T ( Department of Health Science, Oita University of Nursing and Health Science, Oita, Japan.); Yamagami S ( Department of Ophthalmology, Tokyo Women's Medical University Medical Center East, Tokyo, Japan); Fujishima H ( Department of Ophthalmology, Tsurumi University School of Dental Medicine, Kanagawa, Japan.); Kamei Y ( Department of Ophthalmology, Tokyo Women's Medical University Medical Center East, Tokyo, Japan.); Goto M ( Department of Ophthalmology, Tokyo Women's Medical University Medical Center East, Tokyo, Japan.); Takada S ( Department of Ophthalmology, Tokyo Women's Medical University Medical Center East, Tokyo, Japan); Matsubara M ( Department of Ophthalmology, Tokyo Women's Medical University Medical Center East, Tokyo, Japan.) |
| Abstract | OBJECTIVE: Exposure to particulate matter less than 2.5 µm in diameter (PM2.5) is associated with asthma and respiratory symptoms, but little is known about the influence of PM2.5 on allergic conjunctivitis. The purpose of this study was to examine the association of PM2.5 with outpatient attendance for allergic conjunctivitis. METHODS: We conducted a time-series analysis of the association between outpatient attendance for allergic conjunctivitis and PM2.5 levels from May to July (non-pollen season) and from August to October (the autumnal pollen season) in 2012. Air pollution data (including the levels of PM2.5, oxidants, nitric oxide, nitrogen dioxide, nitrogen oxide, carbon monoxide, methane, non-methane hydrocarbons, and total hydrocarbons) and data on the daily weather conditions (temperature, wind speed, and humidity) were collected at a centrally located monitoring station in Tokyo. We calculated weekly average values for the daily number of outpatient visits, as well as the air pollution and weather data, and used the weekly average values for analysis. RESULTS: There was a significant association between the number of outpatient visits for allergic conjunctivitis and the PM2.5 level (r=0.62, p=0.0177) from May to July, while no correlation was found between the number of outpatient visits and any variable assessed from August to November. Multivariate analysis also showed that PM2.5 was a significant predictor of the number of outpatient visits from May to July (odds ratio=9.05, p=0.0463), while there were no significant predictors of the number of outpatient visits from August to October. From May to July, PM2.5 showed a negative correlation with humidity (r=-0.53, p=0.0499). CONCLUSIONS: These findings suggest a possible role of PM2.5 in the development of allergic conjunctivitis during the non-pollen season. This association between PM2.5 and allergic conjunctivitis may have broad public health implications in relation to allergic diseases. |
| ISSN | 00489697 |
| Volume Number | 487 |
| e-ISSN | 18791026 |
| Journal | Science of The Total Environment |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2014-07-15 |
| Publisher Place | Netherlands |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Air Pollutants Analysis Conjunctivitis, Allergic Epidemiology Environmental Monitoring Inhalation Exposure Statistics & Numerical Data Particulate Matter Air Pollution Humans Japan Prevalence Weather Journal Article Research Support, Non-u.s. Gov't Discipline Environmental Science |
| Content Type | Text |
| Resource Type | Article |
| Subject | Environmental Chemistry Waste Management and Disposal Pollution Environmental Engineering |
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