NDLI: Extranodal manifestation of Rosai-Dorfman disease without involvement of lymph nodes.

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Extranodal manifestation of Rosai-Dorfman disease without involvement of lymph nodes.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Grätz, Klaus W. Kruse, Astrid L. D. Gengler, Carole Obwegeser, Joachim A.
Description	Country affiliation: Switzerland Author Affiliation: Kruse AL ( Department of Craniomaxillofacial and Oral Surgery, University of Zurich, Zurich, Switzerland. astrid.kruse@usz.ch)
Abstract	BACKGROUND: Rosai-Dorfman disease is an uncommon sinus histiocytosis with massive lymphadenopathy. Rosai-Dorfman disease without lymphadenopathy is extremely rare. Extranodal pseudotumoral masses can occur--and have been identified and described--in the orbit, skin, bone, and upper respiratory tract. Because of its rareness, Rosai-Dorfman is seldom considered in the clinical differential diagnosis, particularly if extranodal manifestations predominate. METHODS AND RESULTS: We present herein a patient with extranodal manifestation of Rosai-Dorfman disease in the orbit and parotid without typical initial lymph node involvement that reacted on steroid therapy. CONCLUSIONS: The correct diagnosis of this entity with the knowledge that it can occur without lymphadenopathy is important. For these patients, diagnosis must be based on histologic and immunohistopathologic findings after surgical biopsy. Steroid therapy can be used for treatment.
ISSN	10492275
Issue Number	6
Volume Number	21
e-ISSN	15363732
Journal	Journal of Craniofacial Surgery
Language	English
Publisher	Lippincott Williams & Wilkins
Publisher Date	2010-11-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Histiocytosis, Sinus Diagnosis Orbital Diseases Parotid Diseases Adenoma, Pleomorphic Adult Dexamethasone Therapeutic Use Diagnosis, Differential Glucocorticoids Humans Lacrimal Apparatus Diseases Lymph Nodes Pathology Male Maxillary Sinus Paranasal Sinus Diseases Case Reports Journal Article Discipline Medicine Discipline Otorhinolaryngology Discipline Surgery
Content Type	Text
Resource Type	Article Case study
Subject	Otorhinolaryngology Surgery

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