NDLI: Use of a collagen patch for management of pharyngocutaneous fistula after hypopharyngeal reconstruction.

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Use of a collagen patch for management of pharyngocutaneous fistula after hypopharyngeal reconstruction.

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Use of a collagen patch for management of pharyngocutaneous fistula after hypopharyngeal reconstruction.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Lee, Dong Won Chung, Seum Choi, Eun Chang Lee, Won Jai Lew, Dae Hyun
Description	Author Affiliation: Lee DW ( Department of Plastic and Reconstructive Surgery, Yonsei University Health System, Severance Hospital, Seoul, Republic of Korea.)
Abstract	Pharyngocutaneous fistula is one of the fatal complications occurring after head and neck reconstruction with neck node dissection. Even minor salivary leakage from the fistula could cause serious infection and threaten the viability of the transferred flap or even lead to the rupture of jugular vein. In such cases, proper management is difficult, and the chances for recurrence rise. We used a collagen patch (TachoComb) for fistula prevention and treatment. TachoComb, a collagen patch integrated with activated thrombin and fibrinogen, was used to prevent postoperative fistula formation in the initial reconstruction by applying them on sites with a high risk of salivary leakage. The patch was applied to 16 patients who had hypopharyngeal reconstruction, and the results were evaluated and compared with patients who had reconstruction without a collagen patch. A fistula occurred in 1 (6%) of 16 patients who received the collagen patch, whereas it occurred in 6 (14%) of 43 patients who underwent reconstruction without the collagen patch. In addition, the collagen patch was also used to treat postoperative fistula in 2 patients, and the results were successful after a single revision. Our results suggest that the collagen patch can be effective in the prevention and treatment of postoperative fistula after head and neck reconstruction, especially pharynx and cervical esophagus.
ISSN	10492275
Issue Number	6
Volume Number	21
e-ISSN	15363732
Journal	Journal of Craniofacial Surgery
Language	English
Publisher	Lippincott Williams & Wilkins
Publisher Date	2010-11-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Aprotinin Therapeutic Use Collagen Cutaneous Fistula Prevention & Control Fibrinogen Hypopharynx Surgery Pharyngeal Diseases Reconstructive Surgical Procedures Methods Respiratory Tract Fistula Thrombin Tissue Adhesives Aged Administration & Dosage Drug Combinations Free Tissue Flaps Hemostatics Humans Hypopharyngeal Neoplasms Laryngectomy Male Neck Dissection Pharyngectomy Postoperative Complications Retrospective Studies Risk Factors Saliva Surgical Flaps Suture Techniques Case Reports Comparative Study Journal Article Discipline Medicine Discipline Otorhinolaryngology Discipline Surgery
Content Type	Text
Resource Type	Article Case study
Subject	Otorhinolaryngology Surgery

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