NDLI: Cost Analysis of Commonly used Combination of Drugs in Primary Open Angle Glaucoma.

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Cost Analysis of Commonly used Combination of Drugs in Primary Open Angle Glaucoma.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Mirje, Mrutyunjay Bharatha, Ambadasu Kumbar, Shivaprasad Kalakappa Moharir, Gurudatta
Description	Country affiliation: India Author Affiliation: Kumbar SK ( Assistant Professor, Department of Pharmacology, BLDE University's Shri B. M. Patil Medical College , Vijayapura (Bijapur), Karnataka, India .); Mirje M ( Assistant Professor, Department of Pharmacology, BLDE University's Shri B. M. Patil Medical College , Vijayapura (Bijapur), Karnataka, India .); Moharir G ( Lecturer, Department of Pharmacology, BLDE University's Shri B. M. Patil Medical College , Vijayapura (Bijapur), Karnataka, India .); Bharatha A ( Lecturer, Department of Pharmacology, BLDE University's Shri B. M. Patil Medical College , Vijayapura (Bijapur), Karnataka, India .)
Abstract	BACKGROUND: Glaucoma is second cause of blindness in the world. The financial burden on the patient during long-term treatment is immense and affects the compliance to medications, thus visual morbidity. OBJECTIVE: To analyse economic impact of three commonly used drug combinations (Dorzolamide + Timolol = DT; Brimonidine + Timolol = BT; Latanoprost+Timolol = LT) in primary open angle glaucoma. MATERIALS AND METHODS: This observational, prospective study was undertaken at M & J Institute of Ophthalmology, Civil Hospital, Ahmedabad, a western regional institute of Ophthalmology. A total of 257 patients were included in the study. Only101 patients could complete the 6 month follow-up, of which 35, 34 and 32 patients belonged to DT, BT and LT group respectively. Cost of drug, details of the transportation were noted at every visit. Total cost incurred per patient/eye was calculated. Cost effectiveness was calculated by cost per mm Hg IOP (Intra-Ocular Pressure) reduction. RESULTS: Treatment with DT, BT & LT group consumed 8.6%, 4.6% and 7.7% of the per annum income of the family, respectively. Cost of medications per annum (in INR)/eye for DT, BT & LT group were 2562 ± 15.74, 1544 ± 32.06, 3876 ± 73.68 (Mean±SEM) respectively. Additional cost of travelling was different for patients coming from Ahmedabad (Locals) and outsiders (patients coming outside Ahmedabad, India). Outsiders has to bear the brunt of higher transport charges, where they spent an average of Rs. 914, 856 & 933 per annum (5 follow-ups), whereas, Locals spent an average of Rs. 104, 112, 100 for DT, BT & LT group respectively. CONCLUSION: Treatment with BT was found to be most cost-effective among three groups. Drug therapy takes substantial amount from per annum income of family and was an important compliance factor in the treatment of POAG.
ISSN	2249782X
e-ISSN	0973709X
DOI	10.7860/JCDR/2015/12491.5966
Journal	JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Issue Number	5
Volume Number	9
Language	English
Publisher	Dr. Hemant Jain (for Premchand Shantidevi Research Foundation)
Publisher Date	2015-05-01
Publisher Place	India
Access Restriction	Open
Subject Keyword	Discipline Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Clinical Biochemistry

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