NDLI: Heart Rate Changes in Electroacupuncture Treated Polycystic Ovary in Rats.

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Heart Rate Changes in Electroacupuncture Treated Polycystic Ovary in Rats.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Subbiah, Angelie Jessica Ramanathan, Gunasekaran Ramadoss, Mukilan Natrajan, Chidambaranathan
Description	Country affiliation: India Author Affiliation: Ramadoss M ( Senior Lecturer, Department of Physiology, CSI College of Dental Sciences and Research , Madurai, India .); Ramanathan G ( Professor, Department of Physiology, VMKV Medical College , Salem, India .); Subbiah AJ ( Senior lecturer, Department of Anatomy, CSI College of Dental Sciences and Research , Madurai, India .); Natrajan C ( Professor, Department of Pharmacology, KM College of Pharmacy , Madurai, India .)
Abstract	INTRODUCTION: Polycystic Ovary Syndrome (PCOS) is a common metabolic disorder, it affects both humans and animals. It may induce coronary heart disease, obesity and hyperandrogenism. Previous studies show that Low frequency Electroacupuncture (EA) have an effect on PCOS, however the exact pathway is unclear. AIM: To find the effect of EA on autonomic activity of the heart in Estradiol Valerate (EV) induced PCOS rats. MATERIALS AND METHODS: Heart rate variability (HRV) was assessed in 3 groups: 1) Control; 2) PCOS rats; and 3) PCOS rats after EA treatment (n=8 in each group). From the time domain analysis and frequency domain analysis (linear measures) HRV analysis was done. EA stimulation was given at low frequency of 2Hz for 15 min on alternate days for 4-5 weeks. Collected data were statistically analysed using One-Way Analysis of Variance with the application of multiple comparisons of Tukey test. RESULTS: EA treatment group shows significant reduction in Heart Rate (HR) and low frequency, high frequency ratio (LF/HF); and increase in RR interval, Total Power (TP) when compared to PCOS group. CONCLUSION: The study concludes that EA treatment has a significant effect on reducing sympathetic tone and decreasing HR in PCOS.
ISSN	2249782X
e-ISSN	0973709X
DOI	10.7860/JCDR/2016/18303.7395
Journal	JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Issue Number	3
Volume Number	10
Language	English
Publisher	Dr. Hemant Jain (for Premchand Shantidevi Research Foundation)
Publisher Date	2016-03-01
Publisher Place	India
Access Restriction	Open
Subject Keyword	Discipline Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Clinical Biochemistry

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