NDLI: Perimysial fibroblasts of extraocular muscle, as unique as the muscle fibers.

Please wait, while we are loading the content...

Year: 2017 Volume: 58

Year: 2016 Volume: 57

Year: 2015 Volume: 56

Year: 2014 Volume: 56

Year: 2014 Volume: 55

Year: 2013 Volume: 54

Year: 2012 Volume: 53

Year: 2011 Volume: 52

Year: 2010 Volume: 51

Year: 2010 Volume: 51 Issue: 12

Year: 2010 Volume: 51 Issue: 11

Year: 2010 Volume: 51 Issue: 10

Year: 2010 Volume: 51 Issue: 9

Year: 2010 Volume: 51 Issue: 8

Year: 2010 Volume: 51 Issue: 7

Year: 2010 Volume: 51 Issue: 6

Year: 2010 Volume: 51 Issue: 5

Year: 2010 Volume: 51 Issue: 4

Year: 2010 Volume: 51 Issue: 3

Year: 2010 Volume: 51 Issue: 2

Year: 2010 Volume: 51 Issue: 1

Suppression of ICAM-1 in retinal and choroidal endothelial cells by plasmid small-interfering RNAs in vivo.

Using neurogenin to reprogram chick RPE to produce photoreceptor-like neurons.

Identification of vimentin as a novel target of HSF4 in lens development and cataract by proteomic analysis.

A new interocular suppression technique for measuring sensory eye dominance.

Effects of elevated thyroid hormone on adult rabbit extraocular muscles.

Valproic acid-mediated neuroprotection and regeneration in injured retinal ganglion cells.

Inhibition of RhoA signaling with increased Bves in trabecular meshwork cells.

Changes in corneal epithelial layer inflammatory cells in aqueous tear-deficient dry eye.

ERK- and Akt-dependent neuroprotection by erythropoietin (EPO) against glyoxal-AGEs via modulation of Bcl-xL, Bax, and BAD.

Analysis of p53 mutations and the expression of p53 and p21WAF1/CIP1 protein in 15 cases of sebaceous carcinoma of the eyelid.

Dichoptic multifocal pupillography reveals afferent visual field defects in early type 2 diabetes.

Optical characterization of Bangerter foils.

Association of the lumican gene functional 3'-UTR polymorphism with high myopia.

The structural relationship between the microvasculature, neurons, and glia in the human retina.

Inhibition of protein kinase C is not sufficient to prevent or reverse effects of VEGF165 on claudin-1 and permeability in microvascular retinal endothelial cells.

Identification of a novel sodium-coupled oligopeptide transporter (SOPT2) in mouse and human retinal pigment epithelial cells.

Heterozygous loss-of-function variants in CYP1B1 predispose to primary open-angle glaucoma.

Proteomics of uveal melanomas suggests HSP-27 as a possible surrogate marker of chromosome 3 loss.

The effect of trabeculectomy on ocular pulse amplitude.

Mechanisms of corneal tissue cross-linking in response to treatment with topical riboflavin and long-wavelength ultraviolet radiation (UVA).

Stimulation of axon regeneration in the mature optic nerve by intravitreal application of the toll-like receptor 2 agonist Pam3Cys.

Functional and structural changes in a canine model of hereditary primary angle-closure glaucoma.

Constitutive overexpression of pigment epithelium-derived factor inhibition of ocular melanoma growth and metastasis.

The PI3K/Akt and mTOR/P70S6K signaling pathways in human uveal melanoma cells: interaction with B-Raf/ERK.

Perimysial fibroblasts of extraocular muscle, as unique as the muscle fibers.

Clinical evaluation of the proper orthogonal decomposition framework for detecting glaucomatous changes in human subjects.

Role of periostin and interleukin-4 in recurrence of pterygia.

Topical mydriatics affect light-evoked retinal responses in anesthetized mice.

Relationship between static ocular counterroll and Bielschowsky head tilt phenomenon.

Brittle cornea syndrome associated with a missense mutation in the zinc-finger 469 gene.

The effects of a flexible visual acuity-driven ranibizumab treatment regimen in age-related macular degeneration: outcomes of a drug and disease model.

Analysis of postnatal eye development in the mouse with high-resolution small animal magnetic resonance imaging.

Evaluation of retinal nerve fiber layer progression in glaucoma: a study on optical coherence tomography guided progression analysis.

Age-related changes in accommodative dynamics from preschool to adulthood.

In vivo imaging of ocular MCMV infection.

Self-complementary AAV virus (scAAV) safe and long-term gene transfer in the trabecular meshwork of living rats and monkeys.

Bacterial susceptibility to topical antimicrobials and clinical outcome in bacterial keratitis.

Peripheral vascular endothelial dysfunction in glaucomatocyclitic crisis: a preliminary study.

Effects of antioxidants (AREDS medication) on ocular blood flow and endothelial function in an endotoxin-induced model of oxidative stress in humans.

Association of neovascular age-related macular degeneration with specific gene expression patterns in peripheral white blood cells.

Involvement of OCTN2 in the transport of acetyl-L-carnitine across the inner blood-retinal barrier.

Distribution and determinants of ocular biometric parameters in an Asian population: the Singapore Malay eye study.

Ocular gene transfer of active TGF-beta induces changes in anterior segment morphology and elevated IOP in rats.

Soluble EphB4 inhibition of PDGF-induced RPE migration in vitro.

Three-dimensional profile of macular retinal thickness in normal Japanese eyes.

Conjunctival in vivo confocal scanning laser microscopy in patients with Sjögren syndrome.

Inhibition of JAK2/STAT3-mediated VEGF upregulation under high glucose conditions by PEDF through a mitochondrial ROS pathway in vitro.

The involvement of complement factor B and complement component C2 in an Indian cohort with age-related macular degeneration.

Contribution of CD4+CD25+ T cells to the regression phase of experimental autoimmune uveoretinitis.

ARMS2 is a constituent of the extracellular matrix providing a link between familial and sporadic age-related macular degenerations.

Correlation between local stress and strain and lamina cribrosa connective tissue volume fraction in normal monkey eyes.

Functional role of proteolytic processing of recombinant myocilin in self-aggregation.

Reduced myocilin expression in cultured monkey trabecular meshwork cells induced by a selective glucocorticoid receptor agonist: comparison with steroids.

Intravitreal crystalline drug delivery for intraocular proliferation diseases.

Kininogen in autoimmune uveitis: decrease in peripheral blood stream versus increase in target tissue.

Involvement of platelet coagulation and inflammation in the endothelium of Schlemm's canal.

Apical-to-basolateral transcytosis of photoreceptor outer segments induced by lipid peroxidation products in human retinal pigment epithelial cells.

Three-dimensional optokinetic eye movements in the C57BL/6J mouse.

Genetic dependence of central corneal thickness among inbred strains of mice.

Prevention of UV-induced damage to the anterior segment using class I UV-absorbing hydrogel contact lenses.

A novel method for pachymetry mapping of human precorneal tear film using Pentacam with fluorescein.

Combined application of BDNF to the eye and brain enhances ganglion cell survival and function in the cat after optic nerve injury.

Protective effect of clusterin from oxidative stress-induced apoptosis in human retinal pigment epithelial cells.

Evidence for facial nerve-independent mechanisms of blinking in the rat.

In vivo performance of melimine as an antimicrobial coating for contact lenses in models of CLARE and CLPU.

Silent substitution stimulation of S-cone pathway and L- and M-cone pathway in glaucoma.

ACS67, a hydrogen sulfide-releasing derivative of latanoprost acid, attenuates retinal ischemia and oxidative stress to RGC-5 cells in culture.

Correlation between retinal oscillatory potentials and retinal vascular caliber in type 2 diabetes.

Early childhood refractive error and parental history of myopia as predictors of myopia.

Expression of podoplanin and other lymphatic markers in the human anterior eye segment.

In vivo analysis of cone survival in mice.

Cirrus high-definition optical coherence tomography compared with Stratus optical coherence tomography in glaucoma diagnosis.

Flicker ERGs representing chromaticity and luminance signals.

Estimating normative limits of Heidelberg Retina Tomograph optic disc rim area with quantile regression.

Functional role of thymic stromal lymphopoietin in chronic allergic keratoconjunctivitis.

Oscillation of angiogenesis with vascular dropout in diabetic retinopathy by VESsel GENeration analysis (VESGEN).

Oligocone trichromacy: clinical and molecular genetic investigations.

Impact of cataract screening outreach in rural China.

Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury.

The microbead occlusion model: a paradigm for induced ocular hypertension in rats and mice.

Onset and progression of with-the-rule astigmatism in children with infantile nystagmus syndrome.

Year: 2009 Volume: 50

Year: 2008 Volume: 49

Perimysial fibroblasts of extraocular muscle, as unique as the muscle fibers.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Tjoe, Steven Kaminski, Henry J. Leahy, Patrick Kusner, Linda L. Young, Andrew
Description	Country affiliation: United States Author Affiliation: Kusner LL ( Department of Ophthalmology, Saint Louis University, St. Louis, Missouri 63104, USA. lkusner@slu.edu)
Abstract	PURPOSE: Extraocular muscle (EOM) has a distinct skeletal muscle phenotype. The hypothesis for the study was that fibroblasts support the unique EOM phenotype and that perimysial fibroblasts derived from EOM have properties that distinguish them from fibroblasts derived from other skeletal muscle. METHODS: Perimysial fibroblasts from leg muscle (LM-Fibro) and EOM (EOM-Fibro) of mice were derived and maintained in culture. EOM- and LM-Fibro were assessed morphologically and for vimentin, smooth muscle actin, and Thy-1 immunoreactivity. DNA microarray analysis was performed on LM- and EOM-Fibro grown in conditions that support myoblast differentiation. To assess trophic interactions, co-cultures of myoblasts from established cell lines, CL-EOM and CL-LM with, EOM- or LM-Fibro were performed in direct contact and in a permeable filter support culture. The degree of myotube maturation was assessed by the percentage of myotubes with more than three myonuclei per myotube. RESULTS: EOM- and LM-Fibro cells exhibited distinct morphologies. Both cell types proliferated as a monolayer and expressed vimentin. Fifty-five percent (SD 4.4%) of EOM-Fibro were Thy-1 positive compared with only 24% (SD 4.4%) of LM-Fibro. DNA microarray analysis demonstrated differential expression of structural, immune response, and metabolism-related genes between EOM- and LM-Fibro. Co-cultures demonstrated that mature myotube formation in EOM-derived cell lines was supported to a greater extent by EOM-Fibro than by LM-Fibro, compared with CL-EOM grown with LM-Fibro. CONCLUSIONS: Fibroblasts from EOM demonstrate distinct properties that distinguish them from leg muscle-derived fibroblasts. The distinct properties of EOM-Fibro may support the unique EOM phenotype and contribute to their differential involvement in disease.
ISSN	01460404
e-ISSN	15525783
DOI	10.1167/iovs.08-2857
Journal	Investigative Opthalmology & Visual Science
Issue Number	1
Volume Number	51
Language	English
Publisher	Association for Research in Vision and Ophthalmology
Publisher Date	2010-01-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Fibroblasts Cytology Muscle Fibers, Skeletal Oculomotor Muscles Actins Metabolism Animals Antigens, Thy-1 Cell Differentiation Cells, Cultured Coculture Techniques Flow Cytometry Fluorescent Antibody Technique, Indirect Gene Expression Profiling Hindlimb Mice Mice, Inbred C57bl Myoblasts Oligonucleotide Array Sequence Analysis Polymerase Chain Reaction Vimentin Research Support, N.i.h., Extramural Research Support, Non-u.s. Gov't Discipline Ophthalmology
Content Type	Text
Resource Type	Article
Subject	Ophthalmology Sensory Systems Cellular and Molecular Neuroscience

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in