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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Han, Eun Ryung Lee, Jung Jae Yoon, Jong Chul Woo, Se Joon Han, Sang Beom Kim, Ki Woong Hyon, Joon Young |
| Spatial Coverage | Korea |
| Description | Author Affiliation: Kim KW ( Department of Neuropsychiatry,Seoul National University Bundang Hospital, Seongnam, Gyeonggido, Korea.) |
| Abstract | PURPOSE: A population-based cross-sectional study to investigate the association between depression and dry eye disease (DED) in a community-dwelling elderly population. METHODS: The subjects were 657 Korean elders ≥ 65 years of age randomly selected from an official household registration database in Yongin, Korea. DED symptoms were assessed using the six-item Dry Eye Questionnaire. DED signs were evaluated using the Schirmer test, fluorescein stain score, tear film break-up time (BUT). Depression was assessed using the Korean version of the Short Geriatric Depression Scale (SGDS-K). The association between DED and depression was evaluated using logistic linear analyses. RESULTS: The SGDS-K score correlated with the number of positive responses in the Dry Eye Questionnaire (r = 0.229, P < 0.001), but not with tear film break-up time (r = 0.041, P = 0.139) or Schirmer test score (r = 0.048, P = 0.642). In the binary logistic regression model, female sex (P = 0.014), residence in urban areas (P < 0.001), depression (P < 0.001), and Schirmer score of ≤ 5 mm (P = 0.035) were associated with the risk of DED. Depression was associated with the risk of DED (P < 0.001) in the patients with Schirmer score > 5 mm but not in those with Schirmer score ≤ 5 mm (P = 0.290). CONCLUSIONS: Depression was associated with DED symptoms in subjects with normal or mildly reduced tear production. |
| ISSN | 01460404 |
| e-ISSN | 15525783 |
| Journal | Investigative Opthalmology & Visual Science |
| Issue Number | 11 |
| Volume Number | 52 |
| Language | English |
| Publisher | Association for Research in Vision and Ophthalmology |
| Publisher Date | 2011-10-10 |
| Publisher Place | United States |
| Access Restriction | Open |
| Subject Keyword | Depressive Disorder Physiopathology Dry Eye Syndromes Aging Asian Continental Ancestry Group Ethnology Cross-sectional Studies Diagnostic Techniques, Ophthalmological Intelligence Tests Korea Epidemiology Risk Factors Questionnaires Research Support, Non-u.s. Gov't Discipline Ophthalmology |
| Content Type | Text |
| Resource Type | Article |
| Subject | Ophthalmology Sensory Systems Cellular and Molecular Neuroscience |
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