NDLI: Factors affecting corneoscleral topography.

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Factors affecting corneoscleral topography.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Hunt, Chris Wolffsohn, James Young, Graeme Hall, Lee A.
Description	Country affiliation: United kingdom Author Affiliation: Hall LA ( Visioncare Research Ltd., Farnham, United Kingdom. l.hall@visioncare.co.uk)
Abstract	PURPOSE: To evaluate factors affecting corneoscleral profile (CSP) using anterior segment optical coherence tomography (AS-OCT) in combination with conventional videokeratoscopy. METHODS: OCT DATA WERE COLLECTED FROM 204 SUBJECTS OF MEAN AGE 34.9 YEARS (SD: ±15.2 years, range 18-65) using the Zeiss Visante AS-OCT and Medmont M300 corneal topographer. Measurements of corneal diameter (CD), corneal sagittal height (CS), iris diameter (ID), corneoscleral junction angle (CSJ), and scleral radius (SR) were extracted from multiple OCT images. Horizontal visible iris diameter (HVID) and vertical palpebral aperture (PA) were measured using a slit lamp graticule. Subject body height was also measured. Associations were then sought between CSP variables and age, height, ethnicity, sex, and refractive error. RESULTS: Significant correlations were found between age and ocular topography variables of HVID, PA, CSJ, SR, and ID (P < 0.0001), while height correlated with HVID, CD, and ID, and power vector terms with vertical plane keratometry, CD, and CS. Significant differences were noted between ethnicities with respect to CD (P = 0.0046), horizontal and vertical CS (P = 0.0068 and P = 0.0095), and horizontal ID (P = 0.0010). The same variables, with the exception of vertical CS, also varied with sex; horizontal CD (P = 0.0018), horizontal CS (P = 0.0018), and ID (P = 0.0012). Age accounted for the greatest variance in topography variables (36%). CONCLUSIONS: Age is the main factor influencing CSP; this should be taken into consideration in contact lens design, IOL selection, and in the optimization of surgical procedures. Ocular topography also varied with height, sex, ethnicity, and refractive error.
ISSN	01460404
e-ISSN	15525783
Journal	Investigative Opthalmology & Visual Science
Issue Number	5
Volume Number	54
Language	English
Publisher	Association for Research in Vision and Ophthalmology
Publisher Date	2013-05-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Cornea Anatomy & Histology Corneal Topography Sclera Tomography, Optical Coherence Adolescent Anterior Eye Segment Cross-sectional Studies Refractive Errors Pathology Reproducibility Of Results Sex Factors Clinical Trial Research Support, Non-u.s. Gov't Validation Studies Discipline Ophthalmology
Content Type	Text
Resource Type	Article
Subject	Ophthalmology Sensory Systems Cellular and Molecular Neuroscience

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