NDLI: BIOAMBIENT.ES study protocol: rationale and design of a cross-sectional human biomonitoring survey in Spain.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Pollán, Marina Pérez-Gómez, Beatriz Pastor-Barriuso, Roberto Esteban, Marta Castaño, Argelia López-Abente, Gonzalo Román, Javier Cervantes-Amat, Marta Navarro, Carmen Ruiz-Moraga, Montserrat Aragonés, Nuria Calvo, Eva
Organization	BIOAMBIENT.ES
Spatial Coverage	Spain
Description	Country affiliation: Spain Author Affiliation: Pérez-Gómez B ( Environmental and Cancer Epidemiology Unit, National Centre for Epidemiology, Carlos III Institute of Health, Monforte de Lemos 5, 28029 Madrid, Spain. bperez@isciii.es)
Abstract	Human biomonitoring (HBM), defined as the measurement of concentrations of chemicals or of their metabolites in human biological matrices, is considered the method of choice for determining internal exposures in individuals. HBM is part of environmental exposure surveillance systems in several countries. In 2007, the Ministry of Agriculture, Food and Environment promoted BIOAMBIENT.ES project, a national-level HBM study on environmental pollutants carried out in Spain to estimate levels of heavy metals, persistent organic pollutants, and other substances on the Spanish active workforce. BIOAMBIENT.ES is a nationwide cross-sectional study, with a stratified cluster sampling designed to cover all geographical areas, sex and occupational sectors, and aimed to obtain a representative sample of the Spanish workforce. Participants were recruited among people residing in Spain for 5 years or more, which underwent their annual occupational medical check-up in the health facilities of the Societies for Prevention of IBERMUTUAMUR, MUTUALIA, MC-PREVENCIÓN, MUGATRA, UNIMAT PREVENCIÓN, and PREVIMAC (March 2009-July 2010). A total of 1,892 subjects fulfilled the criteria for inclusion, donated biological samples (1,880 blood, 1,770 urine, and 577 hair) and completed a short self-administrated epidemiological questionnaire on environmental and lifestyle-related exposures. Additionally, clinical information from participant's health exams was obtained. This project will provide a first overview of the body burden of selected pollutants in a representative sample of the Spanish-occupied population. This information will be useful to establish reference values of the studied population and, eventually, to evaluate temporal trends and the effectiveness of environmental and health policies.
ISSN	09441344
Issue Number	2
Volume Number	20
e-ISSN	16147499
Journal	Environmental Science and Pollution Research
Language	English
Publisher	Springer
Publisher Date	2013-02-01
Publisher Place	Germany
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Environmental Exposure Analysis Environmental Pollutants Adolescent Adult Cross-sectional Studies Blood Urine Female Humans Male Metals, Heavy Middle Aged Spain Questionnaires Young Adult Journal Article Research Support, Non-u.s. Gov't Discipline Environmental Science Discipline Environmental Chemistry
Content Type	Text
Resource Type	Article
Subject	Environmental Chemistry Health, Toxicology and Mutagenesis Pollution Medicine

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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