NDLI: Highly selective optical and reversible dual-path chemosensor for cyanide detection and its application in live cells imaging.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Torawane, Pritam Tayade, Kundan Kuwar, Anil Srivastava, Rohit Sahoo, Suban K. Kumar Kumawat, Mukesh Keshav, Karunesh
Description	Author Affiliation: Keshav K ( Department of Chemistry, Indian Institute of Technology Bombay, Powai, Mumbai 400076 India.); Torawane P ( School of Chemical Science, North Maharashtra University, Jalgaon 425001, India.); Kumar Kumawat M ( Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India.); Tayade K ( School of Chemical Science, North Maharashtra University, Jalgaon 425001, India.); Sahoo SK ( Department of Applied Chemistry, SV National Institute of Technology, Surat 395007 India.); Srivastava R ( Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India.); Kuwar A ( School of Chemical Science, North Maharashtra University, Jalgaon 425001, India. Electronic address: kuwaras@gmail.com.)
Abstract	A new biocompatible fluorescent receptor 1 was synthesized by conjugating diaminomaleonitrile (DMN) with benzothiazole unit, and characterized by single X-ray. In DMF/water (1:1, v/v), the receptor 1 showed a selectivity turn-on fluorescence at 517nm in the presence of CN . Receptor 1 showed a detection limit down to 0.16µM without any interference from other tested anions. The reversibility and reusability of 1 for the detection of CN ion was also tested for five cycles indicating the probe 1 could be used in a reversible manner. Importantly, the receptor 1 showed excellent cells viability and was successfully applied for the detection of CN in live mouse fibroblast cells L929 cells.
ISSN	09565663
Journal	Biosensors and Bioelectronics
Volume Number	92
e-ISSN	18734235
Language	English
Publisher	Elsevier
Publisher Date	2017-06-15
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Biotechnology
Content Type	Text
Resource Type	Article
Subject	Nanoscience and Nanotechnology Medicine Biophysics Biomedical Engineering Biotechnology Electrochemistry

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