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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Mozumder, Md Salatul Islam Garcia-Gonzalez, Linsey De Wever, Heleen Goormachtigh, Laurens Volcke, Eveline I. P. |
| Description | Author Affiliation: Mozumder MS ( Flemish Institute for Technological Research (VITO), Business Unit Separation and Conversion Technology, Boeretang 200, 2400 Mol, Belgium); Goormachtigh L ( Ghent University, Department of Biosystems Engineering, Coupure Links 653, 9000 Gent, Belgium.); Garcia-Gonzalez L ( Flemish Institute for Technological Research (VITO), Business Unit Separation and Conversion Technology, Boeretang 200, 2400 Mol, Belgium.); De Wever H ( Flemish Institute for Technological Research (VITO), Business Unit Separation and Conversion Technology, Boeretang 200, 2400 Mol, Belgium.); Volcke EI ( Ghent University, Department of Biosystems Engineering, Coupure Links 653, 9000 Gent, Belgium.) |
| Abstract | In this contribution a mechanistic model describing the production of polyhydroxybutyrate (PHB) through pure-culture fermentation was developed, calibrated and validated for two different substrates, namely glucose and waste glycerol. In both cases, non-growth-associated PHB production was triggered by applying nitrogen limitation. The occurrence of some growth-associated PHB production besides non-growth-associated PHB production was demonstrated, although it is inhibited in the presence of nitrogen. Other phenomena observed experimentally and described by the model included biomass growth on PHB and non-linear product inhibition of PHB production. The accumulated impurities from the waste substrate negatively affected the obtained maximum PHB content. Overall, the developed mathematical model provided an accurate prediction of the dynamic behavior of heterotrophic biomass growth and PHB production in a two-phase pure culture system. |
| ISSN | 09608524 |
| Volume Number | 155 |
| e-ISSN | 18732976 |
| Journal | Bioresource Technology |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2014-03-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Bioreactors Biosynthetic Pathways Physiology Cupriavidus Necator Metabolism Hydroxybutyrates Models, Biological Polyesters Biomass Computer Simulation Fermentation Glucose Analysis Glycerol Kinetics Journal Article Discipline Bioresource |
| Content Type | Text |
| Resource Type | Article |
| Subject | Waste Management and Disposal Medicine Environmental Engineering Renewable Energy, Sustainability and the Environment Bioengineering |
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