NDLI: Ribonucleic acid components of murine sarcoma and leukemia viruses.

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Microfluorometric detection of deoxyribonucleic acid replication in human metaphase chromosomes.

Activation of human complement by human lymphoid cells sensitized with histocompatibility alloantisera.

Transcription of simian virus 40. 3. Mapping of 'early' and 'late' species of RNA.

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Specificity of the DNA product of RNA-dependent DNA polymerase in type C viruses. II. Quantitative analysis.

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Marker discrimination in transformation and mutation of pneumococcus.

Suppression of DNA synthesis in hepatoma cells exposed to glucocorticoid hormone in vitro.

A general theory of carcinogenesis.

The presence of ribonucleotides in mature closed-circular mitochondrial DNA.

Production of a noncovalently bonded pentamer of immunoglobulin M: relationship of J chain.

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Can a non-Mendelian mutation affect both chloroplast and mithchondrial ribosomes?

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Homology between type-C viruses of various species as determined by molecular hybridization.

Altered growth behavior of malignant cells associated with changes in externally labeled glycoprotein and glycolipid.

Specific photoaffinity labeling of the adenosine 3':5'-cyclic monophosphate receptor in intact ghosts from human erythrocytes.

Direct evidence of the C-like form of sodium deoxyribonucleate.

Inhibitory action of Ruthenium red on neuromuscular transmission.

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Ribonucleic acid components of murine sarcoma and leukemia viruses.

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Role of cyclic 3':5'-adenosine monophosphate in the early transport changes induced by serum and insulin in quiescent fibroblasts.

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Infectious DNA from herpes simplex virus: infectivity of double-stranded and single-stranded molecules.

Changes in membrane structure associated with cell contact.

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Size and base composition of RNA in supercoiled plasmid DNA.

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Nonrepetitive DNA sequence representation in sea urchin embryo messenger RNA.

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Relatedness of mouse satellite deoxyribonucleic acid to deoxyribonucleic acid of various Mus species.

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Global models of growth and competition.

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Cell-free translation of the globin message within polydisperse high-molecular-weight ribonucleic acid of avian erythrocytes.

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Mitogenic properties of lectin and its chemical dervatives.

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Unique nuclear DNA sequences in the involved tissues of Hodgkin's and Burkitt's lymphomas.

Effect of interferon treatment on cellular messenger RNA.

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Structure of hemoglobin M Boston, a variant with a five-coordinated ferric heme.

Non-Mendelian inheritance of DNA-induced inositol independence in Neurospora.

Purine metabolism in normal and thioguanine-resistant neuroblastoma.

Alkaline phosphatase activity in mouse teratoma.

Poly(inosinic acid)-poly(cytidylic acid) inhibition of DNA synthesis in synchronized HeLa cells.

Statistical mechanics applied to cooperative ligand binding to proteins.

Stereochemical trigger for initiating cooperative interaction of the subunits during the oxygenation of cobaltohemoglobin.

Still more genetic variability in natural populations.

Potentiation by endotoxin of responses associated with increases in calcium conductance.

Cell-surface immunoglobulin human thymus cells and its biosynthesis in vitro.

Alteration in DNA synthetic response of thymocytes from NZB mice of different ages.

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T7 early RNAs and Escherichia coli ribosomal RNAs are cut from large precursor RNAs in vivo by ribonuclease 3.

Synthesis of a large precursor to ribosomal RNA in a mutant of Escherichia coli.

Anaerobic transport in Escherichia coli membrane vesicles.

Scanning transmission electron microscope studies of deep-frozen unfixed muscle correlated with spatial localization of intracellular elements by fluorescent x-ray analysis.

Amino-acid sequence of porcine pepsin.

Tissue-specific transcription of the globin gene in isolated chromatin.

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The nucleotide sequence of the lactose messenger ribonucleic acid transcribed from the UV5 promoter mutant of Escherichia coli.

Nucleotide modification in vitro of the precursor of transfer RNA of Escherichia coli.

The acquisition of specificity in cutaneous sensory neurons: a reconsideration of the integumental specification hypothesis.

A mutant of Escherichia coli with a new, highly efficient promoter for the lactose operon.

Sequence homologies among bacterial and mitochondrial superoxide dismutases.

DNA methylase induced by bacteriophage phiX174.

Effect of the removal of the Y base on the conformation of yeast tRNA.

Mechanism of puromycin action: fate of ribosomes after release of nascent protein chains from polysomes.

Immunological functions of lymphocytes fractionated with antigen-derivatized fibers.

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Ribonucleic acid components of murine sarcoma and leukemia viruses.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Maisel, J. Klement, V. Ostertag, W. Lai, M. M. Duesberg, P.
Abstract	Defective Kirsten murine sarcoma virus was present as leukemia virus pseudotype [Ki-MSV(MLV)] in a 10- to 100-fold excess over its helper, Kirsten murine leukemia virus (Ki-MLV), when the two viruses were propagated in an NRK rat cell line. The s(omega,20) of the fastsedimenting RNA complex of Ki-MLV and of Ki-MSV-(MLV) was 62 S and 55 S, respectively. Gel electrophoresis in buffered aqueous or formamide solution of the dissociated 62S RNA complex of Ki-MLV showed a single major peak of molecular weight about 2.5 x 10(6). Dissociated 55S RNA of Ki-MSV(MLV) was resolved into a major component with a higher electrophoretic mobility than that of Ki-MLV RNA and molecular weight about 2.3 x 10(6). Occasionally, a minor component with the same electrophoretic mobility as Ki-MLV RNA was observed in Ki-MSV(MLV) RNA; it is thought to be the RNA of Ki-MLV present as helper virus in our stocks of Ki-MSV(MLV). The RNA of an endogenous rat C-type RNA virus was electrophoretically different from both Ki-MLV RNA and Ki-MSV(MLV) RNAs. Oligonucleotide fingerprinting of the RNAs digested with RNase T1 indicated that the RNAs of Ki-MSV(MLV) and Ki-MLV are different. However, the extent of the difference between the two RNAs could not be estimated by this method. The heat-dissociated 50-70S RNAs of two other defective murine sarcoma-leukemia viruses; Harvey-MSV(MLV) and Moloney-MSV(MLV) and of defective spleen-focus-forming Friend virus were resolved electrophoretically into two components. The larger components had the same electrophoretic mobility as the RNA of Ki-MLV or Moloney MLV. The smaller were not present in leukemia virus. It is suggested that the small RNA components of the two murine viruses and of Friend virus represent specific genetic information of these replication-defective transforming viruses. Possible relationships between the RNAs of murine leukemia viruses and replication-defective murine sarcoma and Friend viruses are discussed.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	12
Volume Number	70
Language	English
Publisher	National Academy of Sciences
Publisher Date	1973-01-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Gammaretrovirus RNA, Viral Animals Cell Line Centrifugation, Density Gradient Electrophoresis, Polyacrylamide Gel Embryo, Mammalian Friend Murine Leukemia Virus Growth & Development Helper Viruses Kidney Leukemia Virus, Murine Mice Molecular Weight Moloney Murine Leukemia Virus Oligonucleotides Satellite Viruses Spleen Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

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