NDLI: Local interactions in bends of proteins.

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Action of nucleotide phosphotransferase of Escherichia coli on nicotinamide riboside and nicotinamide mononucleotide.

Migration of Escherichia coli dnaB protein on the template DNA strand as a mechanism in initiating DNA replication.

Proof of de novo synthesis of the qa enzymes of Neurospora crassa during induction

Oligomycin-dependent ionophoric protein subunit of mitochondrial adenosinetriphosphatase.

Cellular transformation and differentiation. Effect of Rous sarcoma virus transformation on sulfated proteoglycan synthesis by chicken chondrocytes.

Location of protein(s) involved in oligomycin-induced inhibition of mitochondrial adenosinetriphosphatase near the outer surface of the inner membrane

Elimination of size and charge heterogeneities of human leukocyte interferons by chemical cleavage.

Acyl group and electron pair relay system: a network of interacting lipoyl moieties in the pyruvate and alpha-ketoglutarate dehydrogenase complexes from Escherichia coli.

A light-activated GTPase in vertebrate photoreceptors: regulation of light-activated cyclic GMP phosphodiesterase.

Semisynthetic cytochrome c.

Studies on the mechanism of phosphorylation of synthetic polypeptides by a calf thymus cyclic AMP-dependent protein kinase.

Integration of avian sarcoma virus DNA sequences in transformed mammalian cells.

The RNA of avian acute leukemia virus MC29.

Steroidogenic activity of fragments of adrenocorticotropin with arginine in residue positions 3 and 5.

Replication of viral RNA by a defective interfering vesicular stomatitis virus particle in the absence of helper virus.

Choleragen activation of solubilized adenylate cyclase: requirement for GTP and protein activator for demonstration of enzymatic activity.

Homology between a prolyl hydroxylase subunit and a tissue protein that crossreacts immunologically with the enzyme.

Cyclic AMP, the microtubule-microfilament system, and cancer.

Norepinephrine induces glial-specific enzyme activity in cultured plasma glioma cells.

Tritium suicide selection of mammalian cell mutants defective in the transport of neutral amino acids.

Identification of amber and ochre mutants of the human virus Ad2+ND1.

In vivo and in vitro phosphorylation of rat liver fructose-1,6-bisphosphatase.

Enzyme replacement therapy in Gaucher's disease: preliminary clinical trial of a new enzyme preparation.

Recessive dystrophic epidermolysis bullosa: evidence for an altered collagenase in fibroblast cultures.

Comparison of Epstein-Barr viral DNAs in Burkitt lymphoma biopsy cells and in cells clonally transformed in vitro.

Translation of 35S and of subgenomic regions of avian sarcoma virus RNA.

Friend strain of spleen focus-forming virus is a recombinant between ecotropic murine type C virus and the env gene region of xenotropic type C virus.

Biochemical evidence that MCF murine leukemia viruses are envelope (env) gene recombinants.

Nerve growth factor increases activity of ornithine decarboxylase in superior cervical ganglia of young rats.

Unfolding and refolding occur much faster for a proline-free proteins than for most proline-containing proteins.

Dopaminergic stimulation of cyclic AMP accumulation and parathyroid hormone release from dispersed bovine parathyroid cells.

Activation of guanylate cyclase by superoxide dismutase and hydroxyl radical: a physiological regulator of guanosine 3',5'-monophosphate formation.

Precursor role of arachidonic acid in release of slow reacting substance from rat basophilic leukemia cells.

Human leukocytic pyrogen: purification and development of a radioimmunoassay.

Further study of the effect of enzyme-enzyme interactions on steady-state enzyme kinetics.

Local interactions in bends of proteins.

Structure of proteins: packing of alpha-helices and pleated sheets.

Thermodynamic aspects of the linkage between binding of chloride and oxygen to human hemoglobin.

On the mechanism of genetic recombination: the maturation of recombination intermediates.

On the existence of a steady state in a biological system.

Synthesis of phiX174 viral DNA in vitro depends on phiX replicative form DNA.

Effect of galactose oxidase, with and without prior sialidase treatment, on the viability of erythrocytes in circulation.

Release of ovoperoxidase from sea urchin eggs hardens the fertilization membrane with tyrosine crosslinks.

Nucleotide sequences near the origin of replication of bacteriophage f1.

Chemical basis for brain-specific serine transfer RNAs.

Ionophores stimulate prostaglandin and thromboxane biosynthesis

Structure of a promoter for T7 RNA polymerase.

31P nuclear magnetic relaxation studies of phosphocreatine in intact muscle: determination of intracellular free magnesium.

In vitro biosynthesis of beta-endorphin, gamma-lipoprotein, and beta-lipotropin by the pars intermedia of beef pituitary glands.

Amino acid sequence of a myosin fragment that contains SH-1, SH-2, and Ntau-methylhistidine.

Reovirus mRNA can be covalently crosslinked via the 5' cap to proteins in initiation complexes.

Regulation of growth hormone gene expression: synergistic effects of thyroid and glucocorticoid hormones.

Glycerophospholipid synthesis: improved general method and new analogs containing photoactivable groups.

Use of molecular hybridization to purify and analyze albumin messenger RNA from rat liver.

Translational control by protein kinase in Artemia salina and wheat germ.

Structural gene identification and mapping by DNA-mRNA hybrid-arrested cell-free translation.

Interactions of a photoaffinity analog of GTP with the proteins of microtubules.

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Sequence relationship between long and short repetitive DNA of the rat: a preliminary report.

Loop structures in hybrids of early RNA and the separated strands of adenovirus DNA.

Computer analysis of nucleic acid regulatory sequences.

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Comparative rates of transfer of lipid-linked oligosaccharides to endogenous glycoprotein acceptors in vitro.

Induction and decay of human fibroblast interferon mRNA.

Replication of adenovirus type 2 DNA in vitro.

Surface antigen in early differentiation.

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Microviscosity modulation during the cell cycle of neuroblastoma cells.

MRNA-directed synthesis of catalytically active mouse beta-glucuronidase in Xenopus oocytes.

Hormonal effects on intracellular and secreted casein in cultures of mouse mammary epithelial cells on floating collagen membranes.

Explant cultures of catecholamine-containing neurons from rat brain: biochemical, histofluorescence, and electron microscopic studies.

Comparison of contact-mediated communication in normal and transformed human cells in culture.

Induction of DNA synthesis in BALB/c 3T3 cells by serum components: reevaluation of the commitment process.

Specific factors influencing histotypic aggregation of chick embryo hepatocytes.

Synthesis and secretion of a high molecular weight form of nerve growth factor by skeletal muscle cells in culture.

Cystinotic fibroblasts accumulate cystine from intracellular protein degradation.

Local control of neurite development by nerve growth factor.

Evidence from UV transcription mapping in HeLa cells that heterogeneous nuclear RNA is the messenger RNA precursor.

Bioelectricity and regeneration: large currents leave the stumps of regenerating newt limbs.

Detection of antibody to autologous human leukemia cells by immune adherence assays.

beta-Endorphin: pituitary and adrenal glands modulate its action.

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Role of high-molecular-weight kininogen in surface-binding and activation of coagulation Factor XI and prekallikrein.

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Affinity alkylation labels two subunits of the reduced acetylcholine receptor from mammalian muscle.

Immunological distinction between acetylcholine receptor and the alpha-bungarotoxin-binding component on sympathetic neurons.

Mysterious form of referred sensation in man.

Specific lysine labeling by 18OH- during alkaline cleavage of the alpha-1-antitrypsin-trypsin complex.

Ligand-independent cap formation: redistribution of surface receptors on mouse lymphocytes and thymocytes in hypertonic medium.

Activation of cytotoxic T cells by nonstimulating tumor cells and spleen cell factor(s).

5'-Terminal nucleotide sequence of Escherichia coli lactose repressor mRNA: features of translational initiation and reinitiation sites.

Limited accessibility of chromatin satellite DNA to RNA polymerase from Escherichia coli.

Elongation factor Tu resistant to kirromycin in an Escherichia coli mutant altered in both tuf genes.

Transcription termination at the trp operon attenuators of Escherichia coli and Salmonella typhimurium: RNA secondary structure and regulation of termination.

Helper factor(s) for growth of adeno-associated virus in cells transformed by adenovirus 12.

Differential lateral mobility of IgM and IgG receptors in mouse B lymphocyte membranes.

Nonspecific DNA binding of genome-regulating proteins as a biological control mechanism: measurement of DNA-bound Escherichia coli lac repressor in vivo.

Sequences homologous to ribosomal insertions occur in the Drosophila genome outside the nucleolus organizer.

Gene-sized DNA molecules of the Oxytricha macronucleus have the same terminal sequence.

Genetics of the connective tissue proteins: assignment of the gene for human type I procollagen to chromosome 17 by analysis of cell hybrids and microcell hybrids.

Myosin types during the development of embryonic chicken fast and slow muscles.

Adaptive response due to changes in gene regulation: a study with Drosophila.

A Waldenström macroglobulin that is both a cold agglutinin and a cryoglobulin because it binds N-acetylneuraminosyl residues.

Segregation at a locus determining an immunoglobulin genetic marker for the light chain variable region affects inheritance of expression of an idiotype.

Sedimentation properties of the scrapie agent.

Mouse cytolytic T lymphocytes induced by xenogeneic rat stimulator cells exhibit specificity for H-2 complex alloantigens.

Evidence for an immunoglobulin-dependent antigen-specific helper T cell.

Antigen-specific purification of blocking factors from sera of mice with chemically induced tumors.

Virus-specific proteins in the plasma membrane of cells lytically infected or transformed by pol-oma virus.

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Local interactions in bends of proteins.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Scheraga, H. A. Zimmerman, S. S.
Abstract	Calculated probabilities of bend formation in 47 amino acid sequences of N-acetyl-N'-methylamide dipeptides, determined from a statistical mechanical analysis using empirical conformational energies, were compared with the observed fraction of bends formed in the same 47 dipeptide sequences in the x-ray structures of 20 globular proteins. Agreement between the calculated and observed fraction of bends was found for 26 dipeptides, suggesting that, for those particular dipeptide sequences, local interactions dominate over long-range interactions in determining conformational preference. Seven dipeptide sequences, all of which contained a Gly residue, had a significantly higher calculated than observed bend preference, indicating the strong influence of long-range and/or solvent interactions in those sequences. Of the 14 sequences for which the calculated was significantly less than the observed bend fraction, 13 dipeptide sequences contained at least one polar residue (Ser, Asn, or Asp) and/or an aromatic residue (Phe or Tyr), suggesting that solvent effects may play an important role in dictating the conformation in these sequences. The analysis of dipeptide sequences in the twenty globular proteins also indicated that the 4 leads to 1 hydrogen bond is not a dominant factor in stabilizing bends in proteins, and that most dipeptide sequences are capable of forming several types of bend conformations.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	10
Volume Number	74
Language	English
Publisher	National Academy of Sciences
Publisher Date	1977-01-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Protein Conformation Chemical Phenomena Chemistry Dipeptides Models, Chemical Probability Proteins X-Ray Diffraction Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

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