NDLI: beta-Lipotropin is the major opioid-like peptide of human pituitary and rat pars distalis: lack of significant beta-endorphin.

Please wait, while we are loading the content...

Year: 2017 Volume: 114

Year: 2016 Volume: 113

Year: 2015 Volume: 112

Year: 2014 Volume: 111

Year: 2013 Volume: 110

Year: 2012 Volume: 109

Year: 2011 Volume: 108

Year: 2010 Volume: 107

Year: 2009 Volume: 106

Year: 2008 Volume: 105

Year: 2007 Volume: 104

Year: 2006 Volume: 103

Year: 2005 Volume: 102

Year: 2004 Volume: 101

Year: 2003 Volume: 100

Year: 2002 Volume: 99

Year: 2001 Volume: 98

Year: 2000 Volume: 97

Year: 1999 Volume: 96

Year: 1998 Volume: 95

Year: 1997 Volume: 94

Year: 1996 Volume: 93

Year: 1995 Volume: 92

Year: 1994 Volume: 91

Year: 1993 Volume: 90

Year: 1992 Volume: 89

Year: 1991 Volume: 88

Year: 1990 Volume: 87

Year: 1989 Volume: 86

Year: 1988 Volume: 85

Year: 1987 Volume: 84

Year: 1986 Volume: 83

Year: 1985 Volume: 82

Year: 1984 Volume: 81

Year: 1983 Volume: 80

Year: 1982 Volume: 79

Year: 1981 Volume: 78

Year: 1980 Volume: 77

Year: 1979 Volume: 76

Year: 1978 Volume: 75

Year: 1978 Volume: 75 Issue: 12

Year: 1978 Volume: 75 Issue: 11

Year: 1978 Volume: 75 Issue: 10

Year: 1978 Volume: 75 Issue: 9

Year: 1978 Volume: 75 Issue: 8

Year: 1978 Volume: 75 Issue: 7

Year: 1978 Volume: 75 Issue: 6

Liver cell-mediated mutagenesis of mammalian cells by liver carcinogens.

Conformationally restricted bicyclic analogs of somatostatin.

Mechanism of cholera toxin action: covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system.

Epinephrine-induced elevation of guanosine 3':5'-cyclic monophosphate in isolated fat cells of rat.

The 'sarcoma-specific' region of Moloney murine sarcoma virus 124.

Amino-terminal amino acid sequence of the major structural polypeptides of avian retroviruses: sequence homology between reticuloendotheliosis virus p30 and p30s of mammalian retroviruses.

Inhibition of translation by poliovirus: inactivation of a specific initiation factor.

Purification of the fusion protein of Sendai virus: analysis of the NH2-terminal sequence generated during precursor activation.

Assay for early cytoplasmic effects of the src gene product of Rous sarcoma virus.

Direct evidence for 6-fold symmetry of the herpesvirus hexon capsomere.

Vasoactive intestinal peptide: a potent stimulator of adenosine 3':5'-cyclic monophosphate accumulation in gut carcinoma cell lines in culture.

beta-Lipotropin is the major opioid-like peptide of human pituitary and rat pars distalis: lack of significant beta-endorphin.

Therapy of leishmaniasis: superior efficacies of liposome-encapsulated drugs.

Cell fusion induced by scrapie and Creutzfeldt-Jakob virus-infected brain preparations.

In vitro isolation of stable rat sarcoma viruses.

Ultrastructural localization of gamma-aminobutyric acid receptors in the mammalian central nervous system by means of [3H]muscimol binding.

alpha-Bungarotoxin blocks nicotinic transmission in the avian ciliary ganglion.

Mode of action of colicin Ia: effect of colicin on the Escherichia coli proton electrochemical gradient.

Proposed temperature-dependent conformational transition in D-amino acid oxidase: a differential scanning microcalorimetric study.

Elimination of cooperativity in aspartate transcarbamylase by nitration of a single tyrosine residue.

Heat-stable enterotoxin of Escherichia coli: in vitro effects on guanylate cyclase activity, cyclic GMP concentration, and ion transport in small intestine.

Hemopoietic stem cell transplantation using mouse bone marrow and spleen cells fractionated by lectins.

Beneficial and detrimental actions of histamine H1- and H2-receptor antagonists in circulatory shock.

Biochemical and immunochemical study of lysyl oxidase in experimental hepatic fibrosis in the rat.

Ontogenetic appearance and disappearance of tyrosine hydroxylase and catecholamines in the rat embryo.

Sugar pucker geometries at the intercalation site of propidium diiodide into miniature RNA and DNA duplexes in solution.

Charge stabilization mechanism in the visual and purple membrane pigments.

The beta bulge: a common small unit of nonrepetitive protein structure.

Insulin binding to solubilized material from fat cell membranes: evidence for two binding species.

Phage T4 endonuclease V stimulates DNA repair replication in isolated nuclei from ultraviolet-irradiated human cells, including xeroderma pigmentosum fibroblasts.

Identification of 5,8-oxyretinoic acid isolated from small intestine of vitamin A-deficient rats dosed with retinoic acid.

Purification of the tetrodotoxin-binding component associated with the voltage-sensitive sodium channel from Electrophorus electricus electroplax membranes.

Peroxidized coelenterazine, the active group in the photoprotein aequorin.

Conformation of dopamine at the dopamine receptor.

Selective complexing of the 'nuclear' 5S estradiol receptor by a serum component, 5S-CA.

Inverted repeated DNA from Chinese hamster ovary cells studied with cloned DNA fragments.

Hapten mimic elicits antibodies recognizing prostaglandin E2.

Nitrogenase and nitrogenase reductase associate and dissociate with each catalytic cycle.

DNA unwinding induced by photoaddition of psoralen derivatives and determination of dark-binding equilibrium constants by gel electrophoresis

Mode of action of the hemin-controlled inhibitor of protein synthesis: studies with factors from rabbit reticulocytes.

Nucleosomes associated with newly replicated DNA have an altered conformation.

Amino-terminal sequence analysis of the structural proteins of Sindbis virus.

Structural polymorphism within the amino-terminal region of MM, NN, and MN glycoproteins (glycophorins) of the human erythrocyte membrane.

Mutations of bacteriophage T7 that affect initiation of synthesis of the gene 0.3 protein.

Moleuclar field theory of reversible unfolding of biopolymers.

Determination of molecular motion in membranes using periodic pattern photobleaching.

In vitro differentiation of a fast Na+ conductance in embryonic heart cell aggregates.

Role of estrogen receptor binding and transcriptional activity in the stimulation of hyperestrogenism and nuclear bodies.

De novo induction of a gene product during heterologous epithelial--mesenchymal interactions in vitro.

Induction of murine erythroleukemia differentiation by actinomycin D.

Steroid hormones mediate reversible phenotypic transition between transformed and untransformed states in mouse fibroblasts.

Coordinate control of 3T3 cell proliferation by platelet-derived growth factor and plasma components.

Endocytosis of cholera toxin into neuronal GERL.

Existence of only a single functional pool of adenosine triphosphate in human erythrocytes.

Somatic cell origin of teratocarcinomas.

An ordered sequence of events is required before BALB/c-3T3 cells become committed to DNA synthesis.

Cloned single repeating units of 5S DNA direct accurate transcription of 5S RNA when injected into Xenopus oocytes.

Stepwise mutation model and distribution of allelic frequencies in a finite population.

Genetic analysis of the G1 period: isolation of mutants (or variants) with a G1 perior from a Chinese hamster cell line lacking G1.

Nutritional inhibition of genetically determined renal disease and autoimmunity with prolongation of life in kdkd mice.

Muscarinic cholinergic receptors in murine lymphocytes: demonstration by direct binding.

Primary structure of murine major histocompatibility complex alloantigens: isolation, biochemical characterization, and preliminary alignment of CNBr fragments from the H-2Ib glycoprotein.

Diabetic cataract formation: potential role of glycosylation of lens crystallins.

Endorphins may function in heat adaptation.

Hormonal induction of the secretory immune system in the mammary gland.

Low concentrations of indomethacin inhibit phospholipase A2 of rabbit polymorphonuclear leukocytes.

[Met5]Enkephalin content in brain regions of rats treated with lithium.

Molecular mechanism of mitogen action: processing of receptor induced by epidermal growth factor.

Direct visualization of binding, aggregation, and internalization of insulin and epidermal growth factor on living fibroblastic cells.

Regulation of antibody heterogeneity by suppressor T cells: diminishing suppressor T cell activity increases the number of dinitrophenyl clones in mice immunized with dinitrophenyl-poly(Glu,Lys,Phe) or dinitrophenyl-poly(Glu,Lys,Ala).

Decamethonium both opens and blocks endplate channels.

Reconstitution of an Escherichia coli repair endonuclease activity from the separated uvrA+ and uvrB+/uvrC+ gene products.

Isolation of a mutant of Escherichia coli lacking penicillin-sensitive D-alanine carboxypeptidase IA.

Cold pepsin digestion: a novel method to produce the Fv fragment from human immunoglobulin M.

Transformation-dependent secretion of a low molecular weight protein by murine fibroblasts.

Immunofluorescent localization of a serine protease in rat small intestine.

Potentiation, desensitization, and inversion of response in bacterial sensing of chemical stimuli.

Comparison of Artemia salina and Escherichia coli ribosome structure by electron microscopy.

'Panning' for lymphocytes: a method for cell selection.

Conservation of ribosomal protein binding sites in prokaryotic 16S RNAs.

Regulation of the galactose pathway in Saccharomyces cerevisiae: induction of uridyl transferase mRNA and dependency on GAL4 gene function.

Bone marrow colony-stimulating factor and tumor resistance-enhancing activity of postendotoxin mouse sera.

Modulation of γ-aminobutyric acid transport in nerve endings: Role of extracellular γ-aminobutyric acid and of cationic fluxes

'Nonspecific' cholinesterase and acetylcholinesterase in rat tissues: molecular forms, structural and catalytic properties, and significance of the two enzyme systems.

Adult murine T cells activated in vitro by alpha-fetoprotein and naturally occurring T cells in newborn mice: identity in function and cell surface differentiation antigens.

Pre-proparathyroid hormone; amino acid sequence, chemical synthesis, and some biological studies of the precursor region.

Synthesis of cold-insoluble globulin by cultured calf endothelial cells.

Isolation and characterization of a highly repetitious inverted terminal repeat sequence from Oxytricha macronuclear DNA.

Pseudomonas cytochrome c551 at 2.0 A resolution: enlargement of the cytochrome c family.

Immunological screening method to detect specific translation products.

Chromosomal locations of mouse immunoglobulin genes.

Direct demonstration of immunoglobulin kappa chain RNA in thymus T cells by in situ hybridization.

Stimulation of fetal hemoglobin synthesis in baboons by hemolysis and hypoxia.

Large T1 oligonucleotides of Moloney leukemia virus missing in an env gene recombinant, HIX, are present on an intracellular 21S Moloney viral RNA species.

Clusters of intramembranous particles on cultured myotubes at sites that are highly sensitive to acetylcholine.

Year: 1978 Volume: 75 Issue: 5

Year: 1978 Volume: 75 Issue: 4

Year: 1978 Volume: 75 Issue: 3

Year: 1978 Volume: 75 Issue: 2

Year: 1978 Volume: 75 Issue: 1

Year: 1977 Volume: 74

Year: 1976 Volume: 73

Year: 1975 Volume: 72

Year: 1974 Volume: 71

Year: 1973 Volume: 70

Year: 1972 Volume: 69

Year: 1971 Volume: 68

Year: 1970 Volume: 67

Year: 1970 Volume: 66

Year: 1970 Volume: 65

Year: 1969 Volume: 64

Year: 1969 Volume: 63

Year: 1969 Volume: 62

Year: 1968 Volume: 61

Year: 1968 Volume: 60

Year: 1968 Volume: 59

Year: 1967 Volume: 58

Year: 1967 Volume: 57

Year: 1966 Volume: 56

Year: 1966 Volume: 55

beta-Lipotropin is the major opioid-like peptide of human pituitary and rat pars distalis: lack of significant beta-endorphin.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Liotta, A. S. Krieger, D. T. Suda, T.
Abstract	beta-Lipotropin is the predominant opioid peptide of the human pituitary and rat pars distalis and is present in concentrations essentially equimolar with corticotropin. When freshly, obtained nonfrozen rat anterior pituitaries were homogenized with 0.2 M HCl, approximately 98% of the immunoreactivity detected utilizing an antiserum that crossreacts equally with beta-lipotropin and beta-endorphin coeluted with 125I-labeled human beta-lipotropin upon molecular sieve chromatography. The remainder of the activity eluted with synthetic human beta-endorphin. Similar results were obtained for human pituitary. HCl homogenization of thawed tissue or homogenization of fresh tissue with acetic acid yielded substantially greater concentrations of beta-endorphin and decreased concentrations of beta-lipotropin. In human subjects, acute anterior pituitary stimulation using either insulin-induced hypoglycemia or vasopressin administration was associated with increased plasma beta-lipotropin and corticotropin levels. At the time of peak concentrations, no significant levels of beta-endorphin were detectable. These data indicate the lack of significant amounts of beta-endorphin in human pituitary. Additionally, there appears to be no specific intrapituitary conversion of beta-lipotropin to beta-endorphin.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	6
Volume Number	75
Language	English
Publisher	National Academy of Sciences
Publisher Date	1978-09-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Endorphins Metabolism Pituitary Gland Beta-Lipotropin Adrenocorticotropic Hormone Blood Animals Freezing Insulin Pharmacology Pituitary Gland, Anterior Pituitary Gland, Posterior Temperature Vasopressins Research Support, U.S. Gov't, P.H.S. Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in