NDLI: Globin chain synthesis in single erythroid bursts from cord blood: studies on gamma leads to beta and G gamma leads to A gamma switches.

Please wait, while we are loading the content...

Year: 2017 Volume: 114

Year: 2016 Volume: 113

Year: 2015 Volume: 112

Year: 2014 Volume: 111

Year: 2013 Volume: 110

Year: 2012 Volume: 109

Year: 2011 Volume: 108

Year: 2010 Volume: 107

Year: 2009 Volume: 106

Year: 2008 Volume: 105

Year: 2007 Volume: 104

Year: 2006 Volume: 103

Year: 2005 Volume: 102

Year: 2004 Volume: 101

Year: 2003 Volume: 100

Year: 2002 Volume: 99

Year: 2001 Volume: 98

Year: 2000 Volume: 97

Year: 1999 Volume: 96

Year: 1998 Volume: 95

Year: 1997 Volume: 94

Year: 1996 Volume: 93

Year: 1995 Volume: 92

Year: 1994 Volume: 91

Year: 1993 Volume: 90

Year: 1992 Volume: 89

Year: 1991 Volume: 88

Year: 1990 Volume: 87

Year: 1989 Volume: 86

Year: 1988 Volume: 85

Year: 1987 Volume: 84

Year: 1986 Volume: 83

Year: 1985 Volume: 82

Year: 1984 Volume: 81

Year: 1983 Volume: 80

Year: 1982 Volume: 79

Year: 1981 Volume: 78

Year: 1980 Volume: 77

Year: 1980 Volume: 77 Issue: 12

Year: 1980 Volume: 77 Issue: 11

Year: 1980 Volume: 77 Issue: 10

Year: 1980 Volume: 77 Issue: 9

Year: 1980 Volume: 77 Issue: 8

Year: 1980 Volume: 77 Issue: 7

Year: 1980 Volume: 77 Issue: 6

Year: 1980 Volume: 77 Issue: 5

Year: 1980 Volume: 77 Issue: 4

Year: 1980 Volume: 77 Issue: 3

Year: 1980 Volume: 77 Issue: 2

Year: 1980 Volume: 77 Issue: 1

Chromosomal mutations of Escherichia coli that alter expression of conjugative plasmid functions.

Hypotensive action of parathyroid hormone preparations on rats and dogs.

Tyrosine hydroxylase: a substrate of cyclic AMP-dependent protein kinase.

Complete nucleotide sequence of a 23S ribosomal RNA gene from Escherichia coli.

Globin chain synthesis in single erythroid bursts from cord blood: studies on gamma leads to beta and G gamma leads to A gamma switches.

Monoclonal antibodies specific for carcinoembryonic antigen and produced by two hybrid cell lines.

Substance P enhances cholinergic receptor desensitization in a clonal nerve cell line.

Nerve growth factor stimulates the development of substance P in sensory ganglia.

Method for preparing cultures of central neurons: cytochemical and immunochemical studies.

Major structural proteins of type B, type C, and type D oncoviruses share interspecies antigenic determinants.

Double-stranded RNA inhibits a phosphoprotein phosphatase present in interferon-treated cells.

Mitochondrial membrane biogenesis: identification of a precursor to yeast cytochrome c oxidase subunit II, an integral polypeptide.

Properties of a copper-containing cytochrome c1aa3 complex: a terminal oxidase of the extreme thermophile Thermus thermophilus HB8.

Reovirus-induced modification of cap-dependent translation in infected L cells.

Origin of replication of the DNA of a herpesvirus (pseudorabies).

Unusual features in the nucleotide sequence of a cDNA clone derived from the common region of avian sarcoma virus messenger RNA.

A two-subunit cytochrome c oxidase (cytochrome aa3) from Paracoccus dentrificans.

Cloning DNA sequences from influenza viral RNA segments.

Differential affinities of simian virus 40 large tumor antigen for DNA.

Isolation and characterization of beta-endorphin-like peptides from bovine brains.

Reassembly of protein-lipid complexes into large bilayer vesicles: perspectives for membrane reconstitution.

Methylation of integrated adenovirus type 12 DNA sequences in transformed cells is inversely correlated with viral gene expression.

Isolation of a replication origin complex from Escherichia coli.

Charge selectivity at the lipid-protein interface of membranous Na,K-ATPase.

Selective protection of stereospecific enkephalin and opiate binding against inactivation by N-ethylmaleimide: evidence for two classes of opiate receptors.

In vitro synthesis of the full-length complement of the negative-strand genome RNA of vesicular stomatitis virus.

Sequence of picornavirus RNAs containing a radioiodinated 5'-linked peptide reveals a conserved 5' sequence.

Organization of the recA gene of Escherichia coli.

Alternative method for identifying reconstituted cells.

Target cell specificity of defective avian leukemia viruses: hematopoietic target cells for a given virus type can be infected but not transformed by strains of a different type.

Epidermal growth factor and expression of specific genes: effects on cultured rat pituitary cells are dissociable from the mitogenic response.

Expression of Epstein-Barr virus genes in different cell types after microinjection of viral DNA.

Coupling of active ion transport and aerobic respiratory rate in isolated renal tubules.

Kinetics of decay in the expression of interferon-dependent mRNAs responsible for resistance to virus.

Growth and differentiation of embryonal carcinoma cell line F9 in defined media.

Suspension culture of separated follicles consisting of differentiated thyroid epithelial cells.

Colchicine inhibits epidermal growth factor degradation in 3T3 cells.

Akvr-1, a dominant murine leukemia virus restriction gene, is polymorphic in leukemia-prone wild mice.

Mutant and recombinant avian retroviruses with extended host range.

Isolation and sequence of the gene for iso-2-cytochrome c in Saccharomyces cerevisiae.

Oxidative mechanisms of monocyte-mediated cytotoxicity.

Enhanced drug-metabolizing capacity within liver adjacent to human and rat liver tumors.

Molecular cloning of infectious integrated murine leukemia virus DNA from infected mouse cells.

Generation of oncogenic mouse type C viruses: in vitro selection of carcinoma-inducing variants.

Presynaptic membrane potential affects transmitter release in an identified neuron in Aplysia by modulating the $Ca^{2+}$ and $K^{+}$ currents

Early nerve-muscle synapses in vitro release transmitter over postsynaptic membrane having low acetylcholine sensitivity.

Stress-induced release of prolactin: blockade by dexamethasone and naloxone may indicate beta-endorphin mediation.

Differences in glycosylation patterns of closely related murine leukemia viruses.

Autoradiographic localization of gamma-aminobutyric acid (GABA) receptors in the rat cerebellum.

Host nuclear proteins expressed in simian virus 40-transformed and -infected cells.

Specificity of diffusion channels produced by lambda phage receptor protein of Escherichia coli.

Isozymes of human phosphofructokinase: identification and subunit structural characterization of a new system.

Effect of cleaving interchain disulfide bridges on the radius of gyration and maximum length of anti-poly(D-alanyl) antibodies before and after reaction with tetraalanine hapten.

Inhibition of receptor-mediated clearance of lysine and arginine-modified lipoproteins from the plasma of rats and monkeys.

Arachidonate metabolism via lipoxygenase and 12L-hydroperoxy-5,8,10,14-icosatetraenoic acid peroxidase sensitive to anti-inflammatory drugs.

Linkage analyses of murine immunoglobulin heavy chain and serum prealbumin genes establish their location on chromosome 12 proximal to the T (5;12) 31H breakpoint in band 12F1.

Intervening sequences divide the gene for the constant region of mouse immunoglobulin mu chains into segments, each encoding a domain.

Restoration of active transport of solutes and oxidative phosphorylation by naphthoquinones in irradiated membrane vesicles from Mycobacterium phlei.

Points of contact between histone H1 and the histone octamer.

Structure and function of carboxypeptidase A alpha in supercooled water.

Serum stimulation of phospholipase A2 and prostaglandin release in 3T3 cells is associated with platelet-derived growth-promoting activity.

Monoclonal antibodies to estrophilin: probes for the study of estrogen receptors.

Thermal stability of type I and type III procollagens from normal human fibroblasts and from a patient with osteogenesis imperfecta.

Antisickling activity of amino acid benzyl esters.

Examination of the conventional assumption of internal equilibrium within the states of a biochemical cycle.

Influenza defective interfering viral RNA is formed by internal deletion of genomic RNA.

Photoaffinity labeling of rat androgen binding protein.

Ovalbumin is synthesized in mouse cells transformed with the natural chicken ovalbumin gene.

Phospholipids as the molecular instruments of ion and solute transport in biological membranes.

Diphtheria toxin: nucleotide binding and toxin heterogeneity.

Structure of potato inhibitor complex of carboxypeptidase A at 5.5-A resolution.

Insulin receptor synthesis and turnover in differentiating 3T3-L1 preadipocytes.

Acetone metabolism in mice: increased activity in mice heterozygous for obesity genes.

Analysis of rat heart in vivo by phosphorus nuclear magnetic resonance.

Cell-cell recognition in yeast: purification of Hansenula wingei 21-cell sexual agglutination factor and comparison of the factors from three genera.

Delipidation of bacteriorhodopsin and reconstitution with exogenous phospholipid.

Interaction of 16 alpha-[125I]iodo-estradiol with estrogen receptor and other steroid-binding proteins.

Carboxybiotin translocation mechanisms suggested by diffraction studies of biotin and its vitamers.

Orthorhombic two-dimensional crystal form of purple membrane.

Organ chemiluminescence: noninvasive assay for oxidative radical reactions.

Meiotic synthesis of testis histones in the rat.

Identification of an adhesion factor for chondrocytes.

Arrest and metastasis of blood-borne tumor cells are modified by fusion of plasma membrane vesicles from highly metastatic cells.

Polypeptide composition of squid neurofilaments.

Induction of differentiation of human and murine myeloid leukemia cells in culture by tunicamycin.

Induction of plasminogen activator secretion in macrophages by electrochemical stimulation of the hexose monophosphate shunt with methylene blue.

A selective inhibitor of cell proliferation from normal serum.

Model for capping derived from inhibition of surface receptor capping by free fatty acids.

Fusion of liposomes with mitochondrial inner membranes.

A cytoplasmic clock with the same period as the division cycle in Xenopus eggs.

DNA crosslinking and cytotoxicity in normal and transformed human cells treated with antitumor nitrosoureas.

Differential lectin binding to cellular membranes in the epidermis of the newborn rat.

Lentropin: a factor in vitreous humor which promotes lens fiber cell differentiation.

Phylogenetic analysis of the mycoplasmas.

Triplicated alpha-globin loci in humans.

Antibody-independent activation of the alternative complement pathway by measles virus-infected cells.

Immunoselection of mutants deficient in cell surface glycoproteins encoded by murine erythroleukemia viruses.

Demonstration of a specific mitochondrial isovaleryl-CoA dehydrogenase deficiency in fibroblasts from patients with isovaleric acidemia.

Association of coronary atherosclerosis with hyperapobetalipoproteinemia [increased protein but normal cholesterol levels in human plasma low density (beta) lipoproteins].

Evidence for an important physiological role for calcitonin.

Covalent labeling of protein components of the sodium channel with a photoactivable derivative of scorpion toxin.

Interplexiform cell in cat retina: identification by uptake of gamma-[3H]aminobutyric acid and serial reconstruction.

Spatial frequency specific interaction of dot patterns and gratings.

Correlation between relaxation and automaticity in embryonic heart cell aggregates.

Amino acid side chain conformation in angiotensin II and analogs: correlated results of circular dichroism and 1H nuclear magnetic resonance.

Mitogenic hormone-induced intracellular message: assay and partial characterization of an activator of DNA replication induced by epidermal growth factor.

Physical interaction and activity coupling between two enzymes induced by immobilization of one.

Specific binding of phorbol ester tumor promoters.

Crohn disease lymph node homogenates produce murine lymphoma in athymic mice.

Isolation and characterization of the pigment-protein complexes of Rhodopseudomonas sphaeroides by lithium dodecyl sulfate/polyacrylamide gel electrophoresis.

Contacts between Escherichia coli RNA polymerase and an early promoter of phage T7.

Interspecies homology of nitrogenase genes.

Localization of calmodulin in rat tissues.

I and i antigens of human peripheral blood lymphocytes cocap with receptors for concanavalin A.

Induction of a basement membrane glycoprotein in embryonic kidney: possible role of laminin in morphogenesis.

The RAD52 gene is required for homothallic interconversion of mating types and spontaneous mitotic recombination in yeast.

Model for regulation of the histidine operon of Salmonella.

'Superkiller' mutations suppress chromosomal mutations affecting double-stranded RNA killer plasmid replication in saccharomyces cerevisiae.

Insulin is ubiquitous in extrapancreatic tissues of rats and humans.

[Phe4]somatostatin: a potent, selective inhibitor of growth hormone release.

Production of erythroid-potentiating activity by a human T-lymphoblast cell line.

Cholecystokinin-converting enzymes in brain.

Activation of pyruvate dehydrogenase by direct addition of insulin to an isolated plasma membrane/mitochondria mixture: evidence for generated of insulin's second messenger in a subcellular system.

Year: 1979 Volume: 76

Year: 1978 Volume: 75

Year: 1977 Volume: 74

Year: 1976 Volume: 73

Year: 1975 Volume: 72

Year: 1974 Volume: 71

Year: 1973 Volume: 70

Year: 1972 Volume: 69

Year: 1971 Volume: 68

Year: 1970 Volume: 67

Year: 1970 Volume: 66

Year: 1970 Volume: 65

Year: 1969 Volume: 64

Year: 1969 Volume: 63

Year: 1969 Volume: 62

Year: 1968 Volume: 61

Year: 1968 Volume: 60

Year: 1968 Volume: 59

Year: 1967 Volume: 58

Year: 1967 Volume: 57

Year: 1966 Volume: 56

Year: 1966 Volume: 55

Globin chain synthesis in single erythroid bursts from cord blood: studies on gamma leads to beta and G gamma leads to A gamma switches.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Peschle, C. Covelli, A. Comi, P. Giglioni, B. Gianni, A. M. Barba, P. Ottolenghi, S. Condorelli, M. Polli, E. Migliaccio, G.
Abstract	Erythroid bursts from cord or adult blood were grown in methylcellulose cultures (3 international units of erythropoietin per plate). On day 13, single bursts were picked up and reincubated for 16-24 hr with [3H]leucine. Radioactive globin chains [alpha,beta,G gamma, and A gamma (Ala-136)] were analyzed by either isoelectric focusing on polyacrylamide gels and fluorography or carboxymethylcellulose chromatography. In all cases, alpha to non-alpha globin radioactivity ratios were close to 1. In single cord blood bursts, the values of both gamma-to-beta and G gamma-to-A gamma ratios were spread over a large spectrum and further characterized by a continuous rather than a bimodal distribution. Morever, the G gamma-to-A gamma ratios demonstrated in single bursts appeared to be directly correlated with the respective gamma-to-beta ratios. These data suggest that both the gamma leads to beta and the G gamma leads to A gamma switches are mediated via mechanisms modulating the relative activities of the different genes in the non-alpha globin gene cluster rather than via selection of clones committed to the preferential synthesis of beta and A gamma globins. In contrast with the results obtained with cord blood, individual adult blood bursts synthesize a lower and hence relatively more uniform amount of gamma globin chains.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	1
Volume Number	77
Language	English
Publisher	National Academy of Sciences
Publisher Date	1980-05-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Fetal Blood Metabolism Fetal Hemoglobin Biosynthesis Globins Erythropoiesis Genes Genetic Linkage Hemoglobin A Genetics Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in