NDLI: Differential signal transduction via T-cell receptor CD3 zeta 2, CD3 zeta-eta, and CD3 eta 2 isoforms.

Please wait, while we are loading the content...

Year: 2017 Volume: 114

Year: 2016 Volume: 113

Year: 2015 Volume: 112

Year: 2014 Volume: 111

Year: 2013 Volume: 110

Year: 2012 Volume: 109

Year: 2011 Volume: 108

Year: 2010 Volume: 107

Year: 2009 Volume: 106

Year: 2008 Volume: 105

Year: 2007 Volume: 104

Year: 2006 Volume: 103

Year: 2005 Volume: 102

Year: 2004 Volume: 101

Year: 2003 Volume: 100

Year: 2002 Volume: 99

Year: 2001 Volume: 98

Year: 2000 Volume: 97

Year: 1999 Volume: 96

Year: 1998 Volume: 95

Year: 1997 Volume: 94

Year: 1996 Volume: 93

Year: 1995 Volume: 92

Year: 1994 Volume: 91

Year: 1993 Volume: 90

Year: 1992 Volume: 89

Year: 1991 Volume: 88

Year: 1991 Volume: 88 Issue: 24

Year: 1991 Volume: 88 Issue: 23

Year: 1991 Volume: 88 Issue: 22

Year: 1991 Volume: 88 Issue: 21

Year: 1991 Volume: 88 Issue: 20

Year: 1991 Volume: 88 Issue: 19

Year: 1991 Volume: 88 Issue: 18

Year: 1991 Volume: 88 Issue: 17

Year: 1991 Volume: 88 Issue: 16

Year: 1991 Volume: 88 Issue: 15

Year: 1991 Volume: 88 Issue: 14

Year: 1991 Volume: 88 Issue: 13

Year: 1991 Volume: 88 Issue: 12

Year: 1991 Volume: 88 Issue: 11

Year: 1991 Volume: 88 Issue: 10

Year: 1991 Volume: 88 Issue: 9

Restriction fragment length polymorphism-mediated targeting of the ml-o resistance locus in barley (Hordeum vulgare).

Poliovirus can enter and infect mammalian cells by way of an intercellular adhesion molecule 1 pathway.

Cell cycle-specific effects of lovastatin.

Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone.

Localization of a gene for progressive myoclonus epilepsy to chromosome 21q22.

Cloning of the HLA class II region in yeast artificial chromosomes.

Loss of heterozygosity on the short arm of chromosome 17 is associated with high proliferative capacity and DNA aneuploidy in primary human breast cancer.

Severe von Willebrand disease due to a defect at the level of von Willebrand factor mRNA expression: detection by exonic PCR-restriction fragment length polymorphism analysis.

Characterization of melanotropin-release-inhibiting factor (melanostatin) from frog brain: homology with human neuropeptide Y.

On the association of restriction fragment length polymorphisms across species boundaries.

Efficient immortalization of luminal epithelial cells from human mammary gland by introduction of simian virus 40 large tumor antigen with a recombinant retrovirus.

Interleukin 7 receptor ligation stimulates tyrosine phosphorylation, inositol phospholipid turnover, and clonal proliferation of human B-cell precursors.

Assembly and deacetylation of N-acetylglucosaminyl-plasmanylinositol in normal and affected paroxysmal nocturnal hemoglobinuria cells.

Antibiotic magainins exert cytolytic activity against transformed cell lines through channel formation.

Constitutive and trophoblast-specific expression of a class of bovine interferon genes.

Differential signal transduction via T-cell receptor CD3 zeta 2, CD3 zeta-eta, and CD3 eta 2 isoforms.

Thymic tumorigenesis induced by overexpression of p56lck.

Antibodies that neutralize human beta interferon biologic activity recognize a linear epitope: analysis by synthetic peptide mapping.

cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium.

Thymic targets for Abelson murine leukemia virus are early gamma/delta T lymphocytes.

Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity.

The ATF/CREB transcription factor-binding site in the polymerase beta promoter mediates the positive effect of N-methyl-N'-nitro-N-nitrosoguanidine on transcription.

A subunit common to an IgG Fc receptor and the T-cell receptor mediates assembly through different interactions.

Functional analysis of human cardiac gap junction channel mutants.

Characterization of DNA binding and retinoic acid binding properties of retinoic acid receptor.

Transient occurrence of extrachromosomal DNA of an Arabidopsis thaliana transposon-like element, Tat1.

Improved serodiagnosis of hepatitis C virus infection with synthetic peptide antigen from capsid protein.

Retinoic acid stimulates neurite outgrowth in the amphibian spinal cord.

Calcium/calmodulin-dependent protein kinase mediates a pathway for transcriptional regulation.

Transforming growth factor beta represses the actions of myogenin through a mechanism independent of DNA binding.

Direct spread of reovirus from the intestinal lumen to the central nervous system through vagal autonomic nerve fibers.

Immunofluorescence localization of thyroid hormone receptor protein beta 1 and variant alpha 2 in selected tissues: cerebellar Purkinje cells as a model for beta 1 receptor-mediated developmental effects of thyroid hormone in brain.

Bursting electrical activity in pancreatic beta cells caused by Ca(2+)- and voltage-inactivated Ca2+ channels.

Role for the Epstein-Barr virus nuclear antigen 2 in viral promoter switching during initial stages of infection.

The nuclear protooncogenes c-jun and c-fos as regulators of DNA replication.

Induction of c-fos mRNA and AP-1 DNA-binding activity by cAMP in cooperation with either the adenovirus 243- or the adenovirus 289-amino acid E1A protein.

Identification of intracellular receptor proteins for activated protein kinase C.

Exon amplification: a strategy to isolate mammalian genes based on RNA splicing.

Identification of LRF-1, a leucine-zipper protein that is rapidly and highly induced in regenerating liver.

Analysis of the genes involved in the insulin transmembrane mitogenic signal in Chinese hamster ovary cells, CHO-K1, utilizing insulin-independent mutants.

Neurotrophic protein S100 beta stimulates glial cell proliferation.

UGA is translated as cysteine in pheromone 3 of Euplotes octocarinatus.

The mouse tyrosinase promoter is sufficient for expression in melanocytes and in the pigmented epithelium of the retina.

The Drosophila homologue of vertebrate myogenic-determination genes encodes a transiently expressed nuclear protein marking primary myogenic cells.

Functional analysis of a liver-specific enhancer of the hepatitis B virus.

Dhr6, a Drosophila homolog of the yeast DNA-repair gene RAD6.

A post-transcriptional mechanism contributes to circadian cycling of a per-beta-galactosidase fusion protein.

Nucleokinesis: distinct pattern of cell translocation in response to an autocrine motility factor-like substance or fibronectin.

Guanine nucleotide-binding regulatory proteins in retinal pigment epithelial cells.

Measurement of ligand-induced activation in single viable T cells using the lacZ reporter gene.

Human brain prostaglandin D synthase has been evolutionarily differentiated from lipophilic-ligand carrier proteins.

Splicing of juvenile and adult tau mRNA variants is regulated by thyroid hormone.

Possible catalytic activity of DNA in the reaction between the antitumor drug cis-diamminedichloroplatinum(II) and the intercalator N-methyl-2,7-diazapyrenium.

Long-term inhibition of tumor growth by tumor necrosis factor in the absence of cachexia or T-cell immunity.

Isolation and characterization of two peptides with prolactin release-inhibiting activity from porcine hypothalami.

Trans-seasonal action of androgen in the control of spring courtship behavior in male red-sided garter snakes.

Subtraction inhibition combined with a spiking threshold accounts for cortical direction selectivity.

PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues.

The contribution of DNA single-stranded order to the thermodynamics of duplex formation.

The CDC7 protein of Saccharomyces cerevisiae is a phosphoprotein that contains protein kinase activity.

A site-specific deletion in mitochondrial DNA of Podospora is under the control of nuclear genes.

Cytoplasmic protein binding to highly conserved sequences in the 3' untranslated region of mouse protamine 2 mRNA, a translationally regulated transcript of male germ cells.

Surface appearance and instability of empty H-2 class I molecules under physiological conditions.

Protein kinase C mediates transient spinule-type neurite outgrowth in the retina during light adaptation.

The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.

Localization and synthesis of the hormone-binding regions of the human thyrotropin receptor.

The first milliseconds of the pore formed by a fusogenic viral envelope protein during membrane fusion.

Human monoamine oxidase A and B genes exhibit identical exon-intron organization.

Affinity capture of [Arg8]vasopressin-receptor complex using immobilized antisense peptide.

Alpha B-crystallin is a small heat shock protein.

Vitamin D deficiency causes a selective reduction in deposition of transforming growth factor beta in rat bone: possible mechanism for impaired osteoinduction.

Calculation of protein conformation as an assembly of stable overlapping segments: application to bovine pancreatic trypsin inhibitor.

Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1.

Expression of choline acetyltransferase mRNA in spermatogenic cells results in an accumulation of the enzyme in the postacrosomal region of mature spermatozoa.

Allelic diversity is generated by intraexon sequence exchange at the DRB1 locus of primates.

Proenkephalin A in bone-derived cells.

c-rel activates but v-rel suppresses transcription from kappa B sites.

Sites of interaction of the CCA end of peptidyl-tRNA with 23S rRNA.

Purification of the centromere-specific protein CENP-A and demonstration that it is a distinctive histone.

Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against basic fibroblast growth factor.

Epidermis as the source of ecdysone in an argasid tick.

Niemann-Pick disease: a frequent missense mutation in the acid sphingomyelinase gene of Ashkenazi Jewish type A and B patients.

Anti-Müllerian hormone Bruxelles: a nonsense mutation associated with the persistent Müllerian duct syndrome.

Localization of D1 dopamine receptor mRNA in brain supports a role in cognitive, affective, and neuroendocrine aspects of dopaminergic neurotransmission.

DL-2-amino-4-phosphonobutyric acid does not eliminate 'ON' responses in the visual system of goldfish.

The different tissue transcription patterns of genes for HNF-1, C/EBP, HNF-3, and HNF-4, protein factors that govern liver-specific transcription.

Protein kinase A- and protein kinase C-regulated interaction of plectin with lamin B and vimentin.

Introduction of cytochrome P450IA2 metabolic capability into cell lines genetically matched for DNA repair proficiency/deficiency.

Replication terminator protein of Escherichia coli is a transcriptional repressor of its own synthesis.

Anticodon-dependent aminoacylation of a noncognate tRNA with isoleucine, valine, and phenylalanine in vivo.

Mutations in conserved yeast DNA primase domains impair DNA replication in vivo.

Evidence that nerve growth factor dependence of sympathetic neurons for survival in vitro may be determined by levels of cytoplasmic free Ca2+.

Physiological role of epidermal growth factor on adipose tissue development in vivo.

Theoretical analysis of a physical mapping strategy using random single-copy landmarks.

Identification of genes governing filamentous growth and tumor induction by the plant pathogen Ustilago maydis.

A simple technique for generating probes for RNA in situ hybridization: an adjunct to genome mapping exemplified by the RAG-1/RAG-2 gene cluster.

Alternative splicing contributes to K+ channel diversity in the mammalian central nervous system.

Chlamydia trachomatis developmentally regulated protein is homologous to eukaryotic histone H1.

Tracheal antimicrobial peptide, a cysteine-rich peptide from mammalian tracheal mucosa: peptide isolation and cloning of a cDNA.

Synthesis of large rRNAs by RNA polymerase II in mutants of Saccharomyces cerevisiae defective in RNA polymerase I.

IgM antigen receptor complex contains phosphoprotein products of B29 and mb-1 genes.

Human immunodeficiency virus envelope protein determines the site of virus release in polarized epithelial cells.

Characterization of a posttranslational fucosylation in the growth factor domain of urinary plasminogen activator.

Construction and characterization of a single-chain catalytic antibody.

Protein-protein interactions with the acidic COOH terminus of the single-stranded DNA-binding protein of the bacteriophage T4.

Switching substrate preference of thermophilic xylose isomerase from D-xylose to D-glucose by redesigning the substrate binding pocket.

Local production of tumor necrosis factor encoded by recombinant vaccinia virus is effective in controlling viral replication in vivo.

Primary structure of the merozoite surface antigen 1 of Plasmodium vivax reveals sequences conserved between different Plasmodium species.

The role of Tat in the human immunodeficiency virus life cycle indicates a primary effect on transcriptional elongation.

Acquisition and loss of a neuronal Ca2+/calmodulin-dependent protein kinase during neuronal differentiation.

A heat-labile protein of Chlamydia trachomatis binds to HeLa cells and inhibits the adherence of chlamydiae.

Molecular cloning of a member of a third class of Shaker-family K+ channel genes in mammals. (Journal: Proceedings of the National Academy of Sciences of the United States of America Volume: 88 Issue: 9)

Escherichia coli kgtP encodes an alpha-ketoglutarate transporter.

Year: 1991 Volume: 88 Issue: 8

Year: 1991 Volume: 88 Issue: 7

Year: 1991 Volume: 88 Issue: 6

Year: 1991 Volume: 88 Issue: 5

Year: 1991 Volume: 88 Issue: 4

Year: 1991 Volume: 88 Issue: 3

Year: 1991 Volume: 88 Issue: 2

Year: 1991 Volume: 88 Issue: 1

Two-dimensional life?

Year: 1990 Volume: 87

Year: 1989 Volume: 86

Year: 1988 Volume: 85

Year: 1987 Volume: 84

Year: 1986 Volume: 83

Year: 1985 Volume: 82

Year: 1984 Volume: 81

Year: 1983 Volume: 80

Year: 1982 Volume: 79

Year: 1981 Volume: 78

Year: 1980 Volume: 77

Year: 1979 Volume: 76

Year: 1978 Volume: 75

Year: 1977 Volume: 74

Year: 1976 Volume: 73

Year: 1975 Volume: 72

Year: 1974 Volume: 71

Year: 1973 Volume: 70

Year: 1972 Volume: 69

Year: 1971 Volume: 68

Year: 1970 Volume: 67

Year: 1970 Volume: 66

Year: 1970 Volume: 65

Year: 1969 Volume: 64

Year: 1969 Volume: 63

Year: 1969 Volume: 62

Year: 1968 Volume: 61

Year: 1968 Volume: 60

Year: 1968 Volume: 59

Year: 1967 Volume: 58

Year: 1967 Volume: 57

Year: 1966 Volume: 56

Year: 1966 Volume: 55

Differential signal transduction via T-cell receptor CD3 zeta 2, CD3 zeta-eta, and CD3 eta 2 isoforms.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Bauer, A. Koyasu, S. Howard, F. D. Novick, D. Clayton, L. K. Reinherz, E. L. Mcconkey, D. J.
Description	Author Affiliation: Bauer A ( Laboratory of Immunobiology, Dana-Farber Cancer Institute, Boston, MA.);
Abstract	The T-cell antigen receptor (TCR) consists of an antigen-binding heterodimer, termed Ti, which is noncovalently associated with the invariant CD3 subunits (gamma, delta, epsilon, zeta, and eta). The CD3 zeta and -eta subunits form either homodimeric or heterodimeric structures in turn associated with the other components of the TCR complex. This feature increases the structural complexity of TCRs by creating 'isoforms.' Both CD3 zeta and -eta are thought to play an important role in signal transduction triggered by antigen/major histocompatibility complex. To compare signaling functions of TCR isoforms, MA5.8, a CD3 zeta-eta- variant of the cytochrome c-specific, I-Ek-restricted T-cell hybridoma 2B4.11, was stably transfected with cDNAs encoding CD3 zeta and/or CD3 eta, and resulting clones were characterized. The findings indicate that signals inducing Ca2+ mobilization, phosphatidylinositol turnover, and interleukin 2 production are each transmitted by the above TCR isoforms. In contrast, tyrosine phosphorylation of the CD3 zeta subunit but not the CD3 eta subunit follows TCR stimulation. Given the general importance of tyrosine phosphorylation for receptor signaling, it is likely that this difference between TCR isoforms plays a regulatory role in T-lineage function by qualitatively or quantitatively altering signaling events.
ISSN	00278424
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	9
Volume Number	88
Language	English
Publisher	National Academy of Sciences
Publisher Date	1991-05-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Antigens, Differentiation, T-Lymphocyte Physiology Receptors, Antigen, T-Cell Animals Antigens, CD3 Calcium Cloning, Molecular In Vitro Techniques Interleukin-2 Biosynthesis Macromolecular Substances Mice Phosphatidylinositols Metabolism Phosphorylation Phosphotyrosine Recombinant Proteins Signal Transduction Structure-Activity Relationship Transfection Tyrosine Analogs & Derivatives Multidisciplinary
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in