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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Price, A. Carr, A. J. Arden, N. K. Ashmore, A. M. Glyn-jones, S. Rombach, I. Prieto-alhambra, D. Malak, T. T. Kynaston-pearson, F. Beard, D. Taylor, A. Judge, A. |
| Spatial Coverage | Wales |
| Description | Author Affiliation: Kynaston-Pearson F ( University Hospitals Birmingham NHS Foundation Trust, The Old Queen Elizabeth Hospital, Edgbaston, Birmingham B15 2TH, UK.); |
| Abstract | Objective To determine the extent to which prostheses with no readily available evidence to support their use are being implanted in primary total hip arthroplasty. Design Systematic review of the literature. Data sources The 9th annual report of the National Joint Registry of England and Wales (NJR) was analysed to identify prostheses with an Orthopaedic Data Evaluation Panel rating of “unclassified” or “pre-entry” used in primary total hip arthroplasty in 2011. A systematic review of those prostheses was carried out using PubMed, Cochrane, Embase, OVID, and Google databases. Study selection Prostheses used in primary total hip arthroplasty as published in the NJR’s 9th annual report were analysed. Only literature that included the name of the prosthesis was included. Literature yielded in the search results was excluded if it reported animal, non-orthopaedic, non-total hip arthroplasty, or non-device related studies. Results The systematic review found that 24% (57/235) of all hip replacement implants available to surgeons in the UK have no evidence for their clinical effectiveness. It also shows that 10 617 (7.8%) of the 136 593 components used in primary hip replacements in 2011 were implanted without readily identifiable evidence of clinical effectiveness. These comprised 157 cemented stems (0.5% of 34 655 implanted), 936 (2.8% of 33 367) uncemented stems, 1732 (7.1% of 24 349) cemented cups, and 7577 (17.1% of 44 222) uncemented cups. Conclusions This study shows that a considerable proportion of prostheses available to orthopaedic surgeons have no readily available evidence of clinical effectiveness to support their use. Concern exists about the current system of device regulation, and the need for a revised process for introducing new orthopaedic devices is highlighted. |
| ISSN | 09598138 |
| e-ISSN | 17561833 |
| Journal | BMJ (British Medical Journal) |
| Volume Number | 347 |
| Language | English |
| Publisher | British Medical Journal Publishing Group |
| Publisher Date | 2013-12-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | Open |
| Subject Keyword | Arthroplasty, Replacement, Hip Instrumentation Hip Prosthesis Adverse Effects Bone Cements Evidence-Based Medicine Hip Fractures Surgery Prosthesis Design Prosthesis Failure Risk Factors Wales Research Support, Non-U.S. Gov't Medicine |
| Content Type | Text |
| Resource Type | Article |
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