NDLI: Recent progress in diagnosis and pathomechanism of inclusion body myositis

Please wait, while we are loading the content...

Year: 2017 Volume: 57

Year: 2016 Volume: 56

Year: 2015 Volume: 55

Year: 2014 Volume: 54

Year: 2014 Volume: 54 Issue: 12

My way to 'Keep Pioneering': integrated neuroscience and immunology research produces a paradigm shift for intractable neurological disease

Myasthenia gravis: past, present and future

Diagnosis and care of Charcot-Marie-Tooth disease

Clinical diversity, diagnosis and treatment of hereditary amyloid neuropathy

Clinical practice of hereditary motor neuropathy (HMN) and hereditary sensory and autonomic neuropathy (HSAN)

Magnetoencephalographic study on the disruption of the neural network

Clinical picture and diagnostic criteria of multiple system atrophy

Susceptibility gene in multiple system atrophy (MSA)

Novel therapeutic target in neuromyelitis optica and multiple sclerosis: high mobility group box 1 (HMGB1)

Neurofascin: a novel target for combined central and peripheral demyelination

Role of microglia in inflammatory demyelination lesion in the central nervous system

Neuromuscular disease and sleep disturbance

Sleep disturbance in Parkinson's disease

Headache and sleep disorders

Sleep problems in dementia

Progression from episodic migraine to chronic migraine

Migraine and stroke

Migraine and epilepsy

Cortical spreading depression and pain: a missing link in the pathophysiology of migraine?

Molecular genetics and gene analysis of hereditary spastic paraplegia

Intrathecal baclofen therapy for hereditary spastic paraplegia

Revised Japanese guidelines for the clinical management of bacterial meningitis

Diagnostic and therapeutic strategy for acyclovir-resistant herpes encephalitis

New approach for JC virus detection and its application for PML diagnosis

Identification of NMDA receptor in normal bovine ovary and ovum

Evaluation of autonomic nervous function by assessing baroreceptor reflex

Evaluation of sudomotor function

Sleep and autonomic function: sleep related breathing disorders in Parkinson's disease and related disorders

Diagnosis of small-fiber neuropathy using various autonomic function tests

Clinicopathological features of neuropathy associated with IgG4-related disease

Vasculitic neuropathy: novel classification, diagnosis and treatment

Clinical features and MRI characteristics in neuralgic amyotrophy

Fisher syndrome and Bickerstaff brainstem encephalitis

Gray matter lesions and cognitive impairment in multiple sclerosis

Pathogenesis of cognitive impairment in multiple sclerosis

Exon skipping approach to Duchenne muscular dystorphy

Nonsense readthrough therapy for Duchenne muscular dystrophy

Fasciculation potential and ALS diagnosis

Fasciculation potentials in ALS-significance, and relationship with clinical features

Motor nerve hyperexcitability in ALS: its pathophysiology and treatment

Neuropsychological thinking at everyday clinical practice

Communication disorder in chronic stage stroke patients

Neuropsychology of dementia

Clinical spectrum and treatment strategy in anti-NMDA receptor encephalitis: current status and issues

Anti-NMDA encephalitis in psychiatry; malignant catatonia, atypical psychosis and ECT

Autoimmune encephalitis-update: roles of autoantibodies in the pathogenesis

Recent findings in dermatomyositis-specific autoantibodies

Pathological features of myositis with myositis -specific autoantibodies

Recent progress in diagnosis and pathomechanism of inclusion body myositis

Microglia in neurodegenerative disorders and neuroinflammation

The association of Parkinson's disease pathogenesis with inflammation

Neuroinflammation in amyotrophic lateral sclerosis

Spontaneous seizures in a rat models of multiple prenatal lesioning

Histopathologic features of glia in human epileptogenic brain lesions

Epilepsy and functional brain networks

Recent advance in research of benign adult familial myoclonus epilepsy (BAFME): is BAFME a progressive disorder?

Epilepsy in the elderly

Calpain plays a crucial role in TDP-43 pathology

Neuropathology of hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS)

The new diagnostic methods of CADASIL as differential diagnosis of HDLS

Diagnosis and treatment of dementia: overview

Contribution of molecular imaging research to innovative drug development

Development of disease modifying drugs for dementia-focusing on anti-tau drugs-

Drug development for overcoming dementia in Japan

Progress in diagnosis of and therapy for idiopathic normal-pressure hydrocephalus--Classical view of cerebrospinal production, absorption and bulk flow and its criticism

Progress in diagnosis of and therapy for idiopathic normal-pressure hydrocephalus--Lymphatic drainage of CSF and ISF from the brain: recent concept and hypothesis

Hypothesis of cerebrospinal fluid formation and absorption: from the clinical viewpoint of idiopathic normal pressure hydrocephalus

Intravenous thrombolysis for acute ischemic stroke: past, present and future

Neurologist and emergency neuroendovascular revascularization -training programs for endovascular procedures-

Education for stroke neurologists in neuroendovascular revascularization therapy of acute ischemic stroke

Change in number of residents who plan to specialize in cerebrovascular disease and neurointervention in the Department of Neurology of Kyushu University Hospital

Impact of comprehensive stroke team combined with vascular neurologist, neurosurgeon and endovascular interventionist for acute stroke

Recent progress in diagnosis and pathomechanism of inclusion body myositis

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Aoki, Masashi Suzuki, Naoki Kato, Masaaki Warita, Hitoshi
Description	Author Affiliation: Aoki M ( Department of Neurology, Tohoku University School of Medicine.)
Abstract	Sporadic inclusion body myositis (sIBM) is an intractable and progressive skeletal muscle disease of unknown etiology and without effective treatment. Muscle biopsy typically reveals endomysial inflammation, invasion of mononuclear cells into non-necrotic fibers and rimmed vacuoles, suggesting inflammation and degeneration co-exist as part of the pathomechanism. We estimated the prevalence of sIBM in Japan is 1,000-1,500 in 2003 and an increase in the number of sIBM in Japan in the decade. TDP43 can be a whole mark of the muscle pathology of sIBM patients. Anti-cytosolic 5'-nucleotidase 1A (cN1A) can be a diagnostic marker of sIBM. Elucidation of the pathomechanism of sIBM is the most important to therapy. We'll also review the status of the therapeutics and clinical trials in sIBM.
File Format	HTM / HTML
ISSN	0009918X
e-ISSN	18820654
Journal	Rinsho Shinkeigaku
Issue Number	12
Volume Number	54
Language	Japanese
Publisher	Nihon Shinkei Gakkai
Publisher Date	2014-01-01
Publisher Place	Japan
Access Restriction	Open
Subject Keyword	Discipline Neurology Myositis, Inclusion Body Diagnosis Physiopathology Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Neurology (clinical)

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in