NDLI: Clinical features and MRI characteristics in neuralgic amyotrophy

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Clinical features and MRI characteristics in neuralgic amyotrophy

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Fukushima, Kazuhiro
Description	Author Affiliation: Fukushima K ( Intractable Disease Care Center, Shinshu University Hospital, Shinshu University School of Medicine.)
Abstract	Neuralgic amyotrophy (NA) is a distinct peripheral nervous system (PNS) disorder characterised by sudden attacks of neuropathic pain, usually in a unilateral upper extremity, and patchy paresis with amyotrophy. Under-recognition of NA patients may be frequent because symptoms of NA can be similar to those of common orthopedic disorders. The lesion sites of NA are commonly considered to be brachial plexus (BP) and/or individual branches of the BP. The cause of NA remains unknown. Some evidence support the concept of a complex pathogenesis in NA that includes underlying predisposition and susceptible PNS structures, and it can be triggered by infection, trauma, and strenuous exercise. Typical presentation of NA is characterized by patchy paresis of the periscapular and periglenohumeral muscles. In such cases, STIR-MRI often shows hyperintense signal abnormalities on the affected side of the proximal upper BP. NA is considered to be broad and encompasses a spectrum of atypical presentations, including involvement of lower part of BP, isolated nerves (anterior interosseous nerve or posterior interosseous nerve), or lumbosacral plexuses. Functional prognosis of NA is less favorable than previously assumed. Administration of corticosteroids and intravenous immunoglobulin was described as potential therapeutics for NA, although their efficacy remains unestablished.
File Format	HTM / HTML
ISSN	0009918X
e-ISSN	18820654
Journal	Rinsho Shinkeigaku
Issue Number	12
Volume Number	54
Language	Japanese
Publisher	Nihon Shinkei Gakkai
Publisher Date	2014-01-01
Publisher Place	Japan
Access Restriction	Open
Subject Keyword	Discipline Neurology Brachial Plexus Neuritis Diagnosis Pathology Magnetic Resonance Imaging Etiology Therapy Early Diagnosis Glucocorticoids Administration & Dosage Immunoglobulins, Intravenous
Content Type	Text
Resource Type	Article
Subject	Neurology (clinical)

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