NDLI: Dietary n-3 PUFA and CVD: a review of the evidence.

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Dietary n-3 PUFA and CVD: a review of the evidence.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Mori, Trevor A.
Description	Country affiliation: Australia Author Affiliation: Mori TA ( School of Medicine and Pharmacology, Royal Perth Hospital Unit, University of Western Australia and the Cardiovascular Research Centre, Perth, Western Australia, Australia.)
Abstract	Many clinical and epidemiological studies have shown that the polyunsaturated n-3 fatty acids EPA and DHA from fish and fish oils, provide cardiovascular protection, particularly in the setting of secondary prevention. n-3 Fatty acids beneficially influence a number of cardiometabolic risk factors including blood pressure, cardiac function, vascular reactivity and lipids, as well as having anti-platelet, anti-inflammatory and anti-oxidative actions. They do not appear to adversely interact with other medications such as statins and other lipid-lowering drugs or antihypertensive medications. n-3 Fatty acids have gained widespread usage by general practitioners and clinicians in a number of clinical settings such as pregnancy and infant development, secondary prevention in CHD patients, treatment of dyslipidaemias and haemodialysis patients. Small doses are achievable with consumption of two to three oily fish meals per week or via purified encapsulated preparations now readily available. n-3 Fatty acids, particularly when consumed as fish, should be considered an important component of a healthy diet. The present paper reviews the effects of n-3 fatty acids on cardiometabolic risk factors, concentrating particularly on the evidence from randomised controlled studies in human subjects.
File Format	HTM / HTML
ISSN	00296651
e-ISSN	14752719
Journal	Proceedings of the Nutrition Society
Issue Number	1
Volume Number	73
Language	English
Publisher	Cambridge University Press
Publisher Date	2014-02-01
Publisher Place	Great Britain (UK)
Access Restriction	Open
Subject Keyword	Discipline Nutritional Sciences Cardiovascular Diseases Prevention & Control Diet Fatty Acids, Omega-3 Therapeutic Use Feeding Behavior Animals Etiology Docosahexaenoic Acids Pharmacology Eicosapentaenoic Acid Fish Oils Research Support, N.i.h., Extramural Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Nutrition and Dietetics Medicine

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