NDLI: Extensive screening for edible herbal extracts with potent scavenging activity against superoxide anions.

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Extensive screening for edible herbal extracts with potent scavenging activity against superoxide anions.

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Year: 2008 Volume: 63 Issue: 1

Extensive screening for edible herbal extracts with potent scavenging activity against superoxide anions.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Saito, Keita Kohno, Masahiro Yoshizaki, Fumihiko Niwano, Yoshimi
Description	Country affiliation: Japan Author Affiliation: Saito K ( New Industry Creation Hatchery Center, Tohoku University, Aramaki, Sendai, Japan.)
Abstract	To search for edible herbal extracts with potent antioxidant activity, we conducted a large scale screening based on the superoxide scavenging activity. That is, scavenging activity against superoxide anions were extensively screened from ethanol extracts of approximately 1,000 kinds of herbs by applying an electron spin resonance (ESR)-spin trapping method. Among them we chose four edible herbal extracts with prominently potent ability to reduce the signal intensity of 5,5-dimethyl-1-pyrroline-N-oxide (DMPO)-OOH, a spin adduct formed by DMPO and superoxide anion. They are the extracts from Punica granatum (Peel), Syzygium aromaticum (Bud), Mangifera indica (Kernel), and Phyllanthus emblica (Fruit), and are allowed to be used as foodstuffs according to the Japanese legal regulation. The ESR-spin trapping method coupled with steady state kinetic analysis showed that all of the four extracts directly scavenge superoxide anions, and that the superoxide scavenging potential of any of the extracts was comparable to that of L-ascorbic acid. Furthermore, polyphenol determination indicates that the activity is at least in part attributable to polyphenols. These results with such large scale screening might give useful information when choosing a potent antioxidant as a foodstuff.
File Format	HTM / HTML
ISSN	09219668
Issue Number	2
Volume Number	63
e-ISSN	15739104
Journal	Plant Foods for Human Nutrition
Language	English
Publisher	Springer
Publisher Date	2008-06-01
Publisher Place	Netherlands
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Botany Discipline Nutritional Sciences Antioxidants Metabolism Free Radical Scavengers Plant Extracts Pharmacology Plants, Medicinal Chemistry Superoxides Cyclic N-oxides Electron Spin Resonance Spectroscopy Flavonoids Humans Hydroxyl Radical Phenols Polyphenols Spin Labels Superoxide Dismutase Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Chemistry Food Science

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