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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Bai, W. L. Yin, R. H. Dou, Q. L. Yang, J. C. Zhao, S. J. Ma, Z. J. Yin, R. L. Luo, G. B. Zhao, Z. H. |
| Description | Country affiliation: China Author Affiliation: Bai WL ( College of Animal Science and Veterinary Medicine, Shenyang Agricultural University, Shenyang, China.) |
| Abstract | The aim of this study was to investigate the polymorphism of the CSN1S1 gene promoter region in 4 Chinese yak breeds, and compare the yak CSN1S1 gene promoter region sequences with other ruminants. A Polymerase Chain Reaction-Single Strand Conformation Polymorphism protocol was developed for rapid genotyping of the yak CSN1S1 gene. One hundred fifty-eight animals from 4 Chinese yak breeds were genotyped at the CSN1S1 locus using the protocol developed. A single nucleotide polymorphism of the CSN1S1 gene promoter region has been identified in all yak breeds investigated. The polymorphism consists of a single nucleotide substitution G-->A at position 386 of the CSN1S1 gene promoter region, resulting in two alleles named, respectively, G(386) and A(386), based on the nucleotide at position 386. The allele G(386) was found to be more common in the animals investigated. The corresponding nucleotide sequences in GenBank of yak (having the same nucleotides as allele G(386) in this study), bovine, water buffalo, sheep, and goat had similarity of 99.68%, 99.35%, 97.42%, 95.14%, and 94.19%, respectively, with the yak allele A(386.). |
| File Format | HTM / HTML |
| ISSN | 10495398 |
| Issue Number | 1 |
| Volume Number | 21 |
| e-ISSN | 15322378 |
| Journal | Animal Biotechnology |
| Language | English |
| Publisher | Taylor & Francis |
| Publisher Date | 2010-01-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | Subscribed |
| Subject Keyword | Discipline Zoology Discipline Biotechnology Caseins Genetics Cattle Polymorphism, Single Nucleotide Promoter Regions, Genetic Animals Base Sequence Gene Frequency Genotype Molecular Sequence Data Polymerase Chain Reaction Species Specificity Journal Article |
| Content Type | Text |
| Resource Type | Article |
| Subject | Animal Science and Zoology Bioengineering Biotechnology |
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