NDLI: Associations of A-FABP and H-FABP markers with the content of intramuscular fat in Beijing-You chicken.

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Associations of A-FABP and H-FABP markers with the content of intramuscular fat in Beijing-You chicken.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Ye, M. H. Chen, J. L. Zhao, G. P. Zheng, M. Q. Wen, J.
Description	Country affiliation: China Author Affiliation: Ye MH ( Key Laboratory for Farm Animal Genetic Resources and Utilization of Ministry of Agriculture of China, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.)
Abstract	This study has assessed the association of single nucleotide polymorphisms (SNP) identified in the adipocyte fatty acid binding protein (A-FABP) and heart-type fatty acid binding protein (H-FABP) genes with the content of intramuscular fat (IMF) in a population of male Beijing-You chickens. A previously described SNP in the chicken A-FABP gene had a significant (P < 0.05) effect on IMF content. Chickens inheriting the homozygous BB genotype at A-FABP had a significantly higher content of IMF in thigh muscles and breast muscles than did those inheriting the AA and AB genotypes. A novel SNP, identified here, in the H-FABP gene was also significantly (P < 0.05) associated with IMF content in thigh and breast muscle. Chickens inheriting the genotypes of DD and CD had much higher content of IMF than those inheriting the homozygous genotype of CC. Markers at the A-FABP and H-FABP genes were associated with IMF content in the studied population. Chickens inheriting the BB genotype at A-FABP, along with the CD genotype at H-FABP, produced muscles with a much higher content of IMF when compared with all other genotypes. A weak interaction between A-FABP and H-FABP was detected (P < 0.09) for IMF content in the tested population. The statistical significance of interaction is tentative because of the limited number of observations for some genotypic combinations. Markers identified within the A-FABP and H-FABP genes are suitable for future use in identifying chickens with the genetic potential to produce more desirable muscle with higher IMF content, at least in the population of Beijing-You male chickens.
File Format	HTM / HTML
ISSN	10495398
Issue Number	1
Volume Number	21
e-ISSN	15322378
Journal	Animal Biotechnology
Language	English
Publisher	Taylor & Francis
Publisher Date	2010-01-01
Publisher Place	Great Britain (UK)
Access Restriction	Subscribed
Subject Keyword	Discipline Zoology Discipline Biotechnology Adipose Tissue Metabolism Chickens Genetics Muscle, Skeletal Animals Gene Frequency Genes Genetic Markers Genotype Male Meat Standards Molecular Sequence Data Polymerase Chain Reaction Polymorphism, Single Nucleotide Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Animal Science and Zoology Bioengineering Biotechnology

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