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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Grünberger, Birgit |
| Description | Country affiliation: Austria Author Affiliation: Grünberger B ( Interne Abteilung mit Herzstation und Dialyse, Krankenhaus der Barmherzigen Brüder, Wien, Austria. birgit.gruenberger@bbwien.at) |
| Abstract | Renal cell cancer is the most common form of all malignant renal cancers. The most important exogenic risk factors are smoking and obesity. Most presentations are incidental and, when systemic symptoms occur they are often due to metastases. The mortality rate is still 30% in this disease. The only curative treatment option is surgery. Until recently interferon alpha and/or interleukin-2 were standard treatments in the palliative setting, but efficacy was limited. But in the last years advances could be made. Targeted therapies like sunitinib could demonstrate a significant improvement in progression free survival. Moreover, there are now treatment options even in second line palliative treatment. Nevertheless there are still enough questions to be answered: the optimal sequential therapy, how long should we treat our patients and can we combine theses targeted therapies? Studies to answer all these burning questions are already ongoing. |
| File Format | HTM / HTML |
| ISSN | 00435341 |
| Issue Number | 15-16 |
| Volume Number | 161 |
| e-ISSN | 1563258X |
| Journal | Wiener Medizinische Wochenschrift |
| Language | German |
| Publisher | Springer |
| Publisher Date | 2011-08-01 |
| Publisher Place | Austria |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Medicine Antineoplastic Agents Administration & Dosage Carcinoma, Renal Cell Drug Therapy Kidney Neoplasms Adverse Effects Benzenesulfonates Mortality Pathology Surgery Chemotherapy, Adjuvant Combined Modality Therapy Disease-free Survival Evidence-based Medicine Humans Indoles Molecular Targeted Therapy Neoadjuvant Therapy Neoplasm Staging Nephrectomy Niacinamide Analogs & Derivatives Palliative Care Phenylurea Compounds Practice Guidelines As Topic Prognosis Pyridines Pyrimidines Pyrroles Sulfonamides Journal Article Review |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine |
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