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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Ponholzer, Anton Steinbacher, Ferdinand Madersbacher, Stephan Schramek, Paul |
| Description | Country affiliation: Austria Author Affiliation: Ponholzer A ( Abteilung für Urologie und Andrologie, Krankenhaus der Barmherzigen Brüder, Wien, Austria. antonponholzer@hotmail.com) |
| Abstract | Despite the broad use of PSA-testing in western medicine, still an estimated 1/3 of carcinomas of the prostate (PC) are diagnosed in a locally advanced or metastatic stage. In the current treatment-algorithm for locally advanced PC, radical prostatectomy, external beam radiation therapy (with and without hormonal therapy) and primary androgen deprivation are available. In fact, in a majority of patients treatment of this tumor stage will be a multimodal approach, which has to be discussed individually. For metastatic PC hormonal deprivation therapy is still the gold standard. Beside LHRH-agonists, surgical castration and complete androgen deprivation today LHRH-antagonists represent the different therapeutic options in this tumor stage. Effects on natural course of this disease have to be balanced to the side effects of long-term therapy. Castration-resistant PC is not the object of this overview even though there are a variety of new medical interventions emerging for the treatment of this stage of PC. |
| File Format | HTM / HTML |
| ISSN | 00435341 |
| Issue Number | 15-16 |
| Volume Number | 161 |
| e-ISSN | 1563258X |
| Journal | Wiener Medizinische Wochenschrift |
| Language | German |
| Publisher | Springer |
| Publisher Date | 2011-08-01 |
| Publisher Place | Austria |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Medicine Antineoplastic Agents, Hormonal Therapeutic Use Gonadotropin-releasing Hormone Analogs & Derivatives Orchiectomy Prostatic Neoplasms Pathology Therapy Algorithms Androgen Antagonists Adverse Effects Tumor Markers, Biological Blood Combined Modality Therapy Disease Progression Humans Lymphatic Metastasis Male Neoplasm Staging Prostate-specific Antigen Prostatectomy Mortality Radiotherapy, Adjuvant Randomized Controlled Trials As Topic Survival Rate English Abstract Journal Article Review |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine |
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