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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Collin, Pekka Rondonotti, Emanuele Lundin, Knut Ea Spada, Cristiano Keuchel, Martin Kaukinen, Katri DE Franchis, Roberto Jacobs, Maarten Ajm Villa, Federica Mulder, Chris Jj |
| Description | Country affiliation: Finland Author Affiliation: Collin P ( Department of Gastroenterology and Alimentary Tract Surgery, Medical School, University of Tampere, Tampere, Finland. Pekka.Collin@uta.fi) |
| Abstract | OBJECTIVE: A complete examination of the small intestine is possible by video capsule endoscopy (VCE). The aim of this study was to evaluate current indications for performing VCE in celiac disease. METHODS: In all 84 celiac disease patients on a gluten-free diet who had undergone VCE were enrolled at five centers in Europe. The indications, findings and clinical impact of VCE were recorded by a structured questionnaire. VCE was also carried out in 34 consecutive patients with untreated celiac disease (controls) in another center. RESULTS: Out of the 84 patients, 34 had overt symptoms and small intestinal histology compatible with refractory celiac disease. VCE was normal in 9 patients, and 7 had only proximal and one distal atrophy, 14 had intestinal ulcer and 2 an intestinal stricture. VCE was used in the adjustment of immunosuppressive treatment in 9 patients. In the remaining 50 patients, a VCE was performed because of less severe symptoms, 31 of which had an earlier histological recovery. The VCE showed proximal small bowel atrophy in 21 and distal atrophy in 3 patients, and 3 ulcers were seen. In this group the patients received mainly advice with a view to achieving better dietary compliance. Of the 34 newly detected celiac patients, 4 were normal, 27 proximal and 3 had distal small intestinal atrophy in the VCE. CONCLUSIONS: VCE has a definite impact on the management of refractory sprue. In the remaining patients with established celiac disease, the procedure plays a more limited role. |
| File Format | HTM / HTML |
| ISSN | 17512972 |
| Issue Number | 2 |
| Volume Number | 13 |
| e-ISSN | 17512980 |
| Journal | Journal of Digestive Diseases |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2012-02-01 |
| Publisher Place | Australia |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Gastroenterology Capsule Endoscopy Celiac Disease Diet Therapy Pathology Diet, Gluten-free Intestinal Mucosa Recovery Of Function Adult Aged Aged, 80 And Over Atrophy Female Gastroenterology Trends Humans Male Microvilli Middle Aged Retrospective Studies Young Adult Journal Article Multicenter Study Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Gastroenterology |
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