NDLI: HLA-B*15 subtypes distribution in Han population in Beijing, China, as compared with those of other populations.

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Isolation, polymorphism and expression study of two distinct major histocompatibility complex class II B genes from half-smooth tongue sole (Cynoglossus semilaevis).

HLA-B*15 subtypes distribution in Han population in Beijing, China, as compared with those of other populations.

Changes in frequency of IDDM-associated HLA DQB, CTLA4 and INS alleles.

Human leucocyte antigen class II DRB1 and DQB1 associations in human immunodeficiency virus-infected patients of Mumbai, India.

Year: 2010 Volume: 37 Issue: 2

Year: 2010 Volume: 37 Issue: 1

Year: 2009 Volume: 36

Year: 2008 Volume: 35

Year: 2006 Volume: 33

HLA-B*15 subtypes distribution in Han population in Beijing, China, as compared with those of other populations.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Yang, G. Deng, Y-J Qin, H. Zhu, B-F Chen, F. Shen, C-M Sun, Z-M Chen, L-P Wu, J. Mu, H-F Lucas, R.
Spatial Coverage	Singapore Hong Kong China Taiwan
Description	Country affiliation: United States Author Affiliation: Yang G ( Vascular Biology Center, Medical College of Georgia, Augusta, GA 30912, USA. gyang@mcg.edu)
Abstract	To identify HLA-B15 subtypes distribution in Han population in Beijing, People's Republic of China, 826 unrelated healthy individuals were typed using the polymerase chain reaction-sequence-based typing method. Within the 246 HLA-B15 positive individuals, 29 HLA-B15 alleles were identified, the most predominant of which is B1501 (40.07%), followed by B1502 (12.87%), B1511 (12.87%), B1518 (9.19%) and B1532 (3.31%). The distribution of HLA-B*15 subtype frequencies was compared between the Beijing Han, eight other Chinese ethnic minorities and six Chinese populations covering the mainland of China, Taiwan, Hong Kong and Singapore. A neighbor-joining phylogenetic tree was constructed and revealed that the Beijing Han population clustered into the northern populations group and had a closer relationship with northern Han and Hui than with southern Han or other ethnic minorities. These results thus provide useful information that can be used in anthropology, selection for bone marrow transplantation as well as in disease-association study, such as in carbamazepine (CBZ)-induced Stevens-Johnson syndrome and toxic epidermal necrolysis.
File Format	HTM / HTML
ISSN	17443121
Issue Number	3
Volume Number	37
e-ISSN	1744313X
Journal	International Journal of Immunogenetics
Language	English
Publisher	Wiley-Blackwell
Publisher Date	2010-06-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Genetics Discipline Immunology Asian Continental Ancestry Group Ethnic Groups Hla-b Antigens Genetics Polymorphism, Genetic China Ethnology Cluster Analysis Gene Frequency Genetics, Population Heterozygote Detection Hong Kong Humans Phylogeny Singapore Taiwan Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Genetics Molecular Biology Immunology Genetics (clinical)

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HLA-B*15 subtypes distribution in Han population in Beijing, China, as compared with those of other populations.

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Distribution of HLA-A, -B, -Cw, and -DRB1 alleles and haplotypes in an isolated Han population in Southwest China.

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