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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Altamura, A. C. De Gaspari, I. F. Rovera, C. Colombo, E. M. Mauri, M. C. Fedele, L. |
| Description | Country affiliation: Italy Author Affiliation: Altamura AC ( Department of Psychiatry, IRCCS Foundation Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.) |
| Abstract | OBJECTIVE: The objective of our study was to analyze the efficacy and the safety of SSRIs during pregnancy. METHODS: A group of 30 pregnant women affected by Major Depressive Disorder by SCID I interview (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Text Revision criteria) and treated with selective serotonin reuptake inhibitor (SSRI) were included in the study. They were matched to a comparison group of 26 pregnant women. RESULTS: There were no statistically significant differences in any of the pregnancy outcomes of interest between the treated women and comparison group. There was no statistically significant association in newborns of women treated with an SSRI and the control group in the first and fifth minute Apgar score, and no newborns were admitted to neonatal Intensive Care Units. CONCLUSIONS: No definitive association between use of SSRIs during pregnancy and an increased risk of birth defects or other adverse outcomes could be found. |
| File Format | HTM / HTML |
| ISSN | 08856222 |
| Issue Number | 1 |
| Volume Number | 28 |
| e-ISSN | 10991077 |
| Journal | Human Psychopharmacology: Clinical and Experimental |
| Language | English |
| Publisher | Wiley |
| Publisher Date | 2013-01-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Psychopharmacology Depressive Disorder, Major Drug Therapy Epidemiology Pregnancy Complications Pregnancy Outcome Serotonin Uptake Inhibitors Therapeutic Use Adolescent Adult Female Humans Infant, Newborn Pregnancy Adverse Effects Ultrasonography, Prenatal Methods Young Adult Controlled Clinical Trial Journal Article |
| Content Type | Text |
| Resource Type | Article |
| Subject | Neurology Neurology (clinical) Pharmacology (medical) Psychiatry and Mental Health |
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