NDLI: Clastogenic effects of inorganic arsenic salts on human chromosomes in vitro.

Please wait, while we are loading the content...

Year: 2017 Volume: 40

Year: 2016 Volume: 39

Year: 2015 Volume: 38

Year: 2014 Volume: 37

Year: 2013 Volume: 36

Year: 2012 Volume: 35

Year: 2011 Volume: 34

Year: 2010 Volume: 33

Year: 2009 Volume: 32

Year: 2009 Volume: 32 Issue: 4

Year: 2009 Volume: 32 Issue: 3

Year: 2009 Volume: 32 Issue: 2

Arsenic-induced oxidative cerebral disorders: protection by taurine.

Effect of methotrexate on the survival of human lymphocyte cultures carrying MTHFR 677 (C>T) and MTHFR 1298 (A>C) mutations.

Effect of exposure to fentanyl aerosol in mice on breathing pattern and respiratory variables.

A new illicit opioid dependence outbreak, evidence for a combination of opioids and steroids.

GT1-7 cell-based cytoxicity screening assay on 96-well microplates as a platform for the safety assessment of genetically modified Gerbera hybrida extracts.

A comparison of neuroprotective efficacy of newly developed oximes (K203, K206) and commonly used oximes (obidoxime, HI-6) in tabun-poisoned rats.

Cell protection induced by Acacia salicina extracts: inhibition of genotoxic damage and determination of its antioxidant capacity.

Developmental toxicity of dibutyltin dichloride given on three consecutive days during organogenesis in cynomolgus monkeys.

Apoptotic death mode of mitomycin C-treated HeLa cells and cellular localization of mitomycin C-induced P-glycoprotein.

Clastogenic effects of inorganic arsenic salts on human chromosomes in vitro.

Year: 2009 Volume: 32 Issue: 1

Year: 2008 Volume: 31

Clastogenic effects of inorganic arsenic salts on human chromosomes in vitro.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Chakraborty, Tulika De, Madhusnata
Description	Country affiliation: India Author Affiliation: Chakraborty T ( Vivekananda Institute of Medical Sciences, Ramakrishna Mission Seva Pratishthan, Kolkata, India. tuli_8@rediffmail.com)
Abstract	Arsenic is well documented as a paradoxical human carcinogen. In West Bengal, several million people were found to be arsenic affected who were exposed to this metalloid principally through drinking water. The arsenic-contaminated drinking water contains both trivalent as well as pentavalent arsenic. In this study, the comparative in vitro cytogenetic effects of two inorganic salts of arsenic, trivalent sodium arsenite (NaAsO(2)) and pentavalent sodium arsenate (Na(2)HAsO4) in three different concentrations, were screened for damage to chromosome and cell division following exposure to human lymphocyte culture. The chromosome-breaking activities in cultured lymphocytes were significantly higher for the compounds with trivalent (NaAsO(2)) than with pentavalent arsenic (Na(2)HAsO(4)), as reflected by the higher chromosomal aberration percentage in the similar doses used. It suggests that sodium arsenite was considerably more clastogenic than sodium arsenate. Moreover, increases in chromosomal aberrations were proportional with the increased dose of exposure for both trivalent and pentavalent forms of arsenic.
File Format	HTM / HTML
ISSN	01480545
Issue Number	2
Volume Number	32
e-ISSN	15256014
Journal	Drug and Chemical Toxicology
Language	English
Publisher	Taylor & Francis
Publisher Date	2009-01-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Toxicology Arsenic Toxicity Cell Division Drug Effects Chromosome Aberrations Chemically Induced Lymphocytes Water Pollutants, Chemical Animals Arsenates Arsenites Cells, Cultured Humans Pathology Ultrastructure Mutagens Oxidative Stress Sodium Compounds Sulfhydryl Reagents Water Supply Analysis Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Health, Toxicology and Mutagenesis Public Health, Environmental and Occupational Health Toxicology Pharmacology Chemical Health and Safety

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in