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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Martin, Richard J. Di Fiore, Juliann M. Walsh, Michele C. |
| Description | Author Affiliation: Martin RJ ( Division of Neonatology, Department of Pediatrics, Rainbow Babies & Children's Hospital, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Suite RBC 3100, Cleveland, OH 44106-6010, USA. Electronic address: rxm6@case.edu.); Di Fiore JM ( Division of Neonatology, Department of Pediatrics, Rainbow Babies & Children's Hospital, Case Western Reserve University, 11100 Euclid Avenue, Suite RBC 3100, Cleveland, OH 44106-6010, USA.); Walsh MC ( Division of Neonatology, Department of Pediatrics, Rainbow Babies & Children's Hospital, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Suite RBC 3100, Cleveland, OH 44106-6010, USA.) |
| Abstract | Hypoxic episodes are troublesome components of bronchopulmonary dysplasia (BPD) in preterm infants. Immature respiratory control seems to be the major contributor, superimposed on abnormal respiratory function. Relatively short respiratory pauses may precipitate desaturation and bradycardia. This population is predisposed to pulmonary hypertension; it is likely that pulmonary vasoconstriction also plays a role. The natural history has been well-characterized in the preterm population at risk for BPD; however, the consequences are less clear. Proposed associations of intermittent hypoxia include retinopathy of prematurity, sleep disordered breathing, and neurodevelopmental delay. Future study should address whether these associations are causal relationships. |
| File Format | HTM / HTML |
| ISSN | 00955108 |
| Issue Number | 4 |
| Volume Number | 42 |
| e-ISSN | 15579840 |
| Journal | Clinics in Perinatology |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2015-12-01 |
| Publisher Place | United States |
| Access Restriction | Subscribed |
| Subject Keyword | Discipline Perinatology Apnea Physiopathology Bronchopulmonary Dysplasia Hypertension, Pulmonary Anoxia Metabolism Bradycardia Humans Infant, Newborn Infant, Premature Respiration Disorders Journal Article Research Support, N.i.h., Extramural Review |
| Content Type | Text |
| Resource Type | Article |
| Subject | Pediatrics, Perinatology and Child Health Obstetrics and Gynecology |
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