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A probabilistic and individualized approach for predicting treatment gains: an extension and application to anxiety disordered youth.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Beidas, Rinad S. Lindhiem, Oliver Brodman, Douglas M. Swan, Anna Carper, Matthew Cummings, Colleen Kendall, Philip C. Albano, Anne Marie Rynn, Moira Piacentini, John McCracken, James Compton, Scott N. March, John Walkup, John Ginsburg, Golda Keeton, Courtney P. Birmaher, Boris Sakolsky, Dara Sherrill, Joel
Description	Author Affiliation: Beidas RS ( University of Pennsylvania, School of Medicine. Electronic address: rbeidas@upenn.edu.); Lindhiem O ( University of Pittsburgh, School of Medicine.); Brodman DM ( Temple University.); Swan A ( Temple University.); Carper M ( Temple University.); Cummings C ( Temple University.); Kendall PC ( Temple University.); Albano AM ( Columbia University.); Rynn M ( Columbia University.); Piacentini J ( UCLA.); McCracken J ( UCLA.); Compton SN ( Duke Child and Family Study Center.); March J ( Duke Child and Family Study Center.); Walkup J ( Cornell University.); Ginsburg G ( Johns Hopkins University.); Keeton CP ( Johns Hopkins University.); Birmaher B ( University of Pittsburgh, School of Medicine.); Sakolsky D ( University of Pittsburgh, School of Medicine.); Sherrill J ( National Institute of Mental Health.)
Abstract	The objective of this study was to extend the probability of treatment benefit method by adding treatment condition as a stratifying variable, and illustrate this extension of the methodology using the Child and Adolescent Anxiety Multimodal Study data. The probability of treatment benefit method produces a simple and practical way to predict individualized treatment benefit based on pretreatment patient characteristics. Two pretreatment patient characteristics were selected in the production of the probability of treatment benefit charts: baseline anxiety severity, measured by the Pediatric Anxiety Rating Scale, and treatment condition (cognitive-behavioral therapy, sertraline, their combination, and placebo). We produced two charts as exemplars which provide individualized and probabilistic information for treatment response and outcome to treatments for child anxiety. We discuss the implications of the use of the probability of treatment benefit method, particularly with regard to patient-centered outcomes and individualized decision-making in psychology and psychiatry.
File Format	HTM / HTML
ISSN	00057894
e-ISSN	18781888
DOI	10.1016/j.beth.2013.05.001
Journal	Behavior Therapy
Issue Number	1
Volume Number	45
Language	English
Publisher	Elsevier
Publisher Date	2014-01-01
Publisher Place	Great Britain (UK)
Access Restriction	Open
Subject Keyword	Discipline Therapeutics Discipline Behavioral Sciences Anti-anxiety Agents Therapeutic Use Anxiety Disorders Therapy Cognitive Therapy Sertraline Adolescent Drug Therapy Psychology Combined Modality Therapy Research Support, N.i.h., Extramural
Content Type	Text
Resource Type	Article
Subject	Clinical Psychology

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