NDLI: Electrocardiographic abnormalities in centenarians and octogenarians: a case-matched study.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Moubarak, Ghassan Algalarrondo, Vincent Badenco, Nicolas Guiot, Aurélie Guillausseau, Pierre-Jean Bergmann, Jean-François Bardin, Thomas Leenhardt, Antoine Solal, Alain Cohen
Spatial Coverage	Paris
Description	Country affiliation: France Author Affiliation: Moubarak G ( Department of Cardiac Pacing and Electrophysiology, Hospital Paris Saint-Joseph, Paris, France. ghassan.moubarak@gmail.com)
Abstract	BACKGROUND: Centenarians have been proposed as a model of successful aging but recent studies suggest a high prevalence of cardiovascular diseases. Some findings on their electrocardiograms (ECGs) are simply age-related and others mirror underlying diseases. We aimed to identify ECG features truly associated with extreme age. METHODS: Retrospective analysis of 55 centenarians hospitalized between January 2000 and June 2010. Each centenarian was matched with three octogenarians according to gender, presence of hypertension, aortic stenosis, heart failure, and ischemic heart disease. RESULTS: A history of hypertension was present in 32 (58%) centenarians, aortic stenosis in 6 (11%), heart failure in 8 (15%), and ischemic heart disease in 6 (11%). Centenarians had a higher heart rate than octogenarians (81 ± 15 bpm vs. 72 ± 15 bpm, respectively, P < 0.001) but were less frequently on beta-blockers (7% vs. 36%, respectively, P < 0.001). Centenarians displayed more frequently atrial premature beats than octogenarians (18% vs. 3%, respectively, P < 0.001) but tended to have less atrial fibrillation (15% vs. 22% respectively, P = 0.21). Centenarians had more frequently left QRS axis deviation (48% vs. 28%, P = 0.009) and Q waves (14% vs. 1%, P = 0.02). QT interval was more prolonged in centenarians (446 ± 42 ms vs. 429 ± 39 ms, P = 0.008). Two centenarians (4%) and 24 (15%) octogenarians had a strictly normal ECG (P = 0.02). CONCLUSIONS: Abnormal ECG is a common finding in centenarians, with different characteristics than in younger elderly individuals. These differences are unrelated to the presence of cardiac diseases.
File Format	HTM / HTML
ISSN	1082720X
Issue Number	4
Volume Number	17
e-ISSN	1542474X
Journal	Annals of Noninvasive Electrocardiology
Language	English
Publisher	Wiley
Publisher Date	2012-10-01
Publisher Place	United States
Access Restriction	Subscribed
Subject Keyword	Discipline Cardiology Electrocardiography Statistics & Numerical Data Geriatric Assessment Methods Heart Diseases Epidemiology Physiopathology Heart Rate Age Factors Aged, 80 And Over Arrhythmias, Cardiac Female Humans Male Observer Variation Paris Retrospective Studies Journal Article
Content Type	Text
Resource Type	Article
Subject	Physiology (medical) Cardiology and Cardiovascular Medicine

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