NDLI: Development and validation of a prognostic index for risk stratification of patients with early repolarization.

Please wait, while we are loading the content...

Year: 2016 Volume: 21

Year: 2015 Volume: 20

Year: 2014 Volume: 19

Year: 2013 Volume: 18

Year: 2012 Volume: 17

Year: 2012 Volume: 17 Issue: 4

Magnetocardiography for the diagnosis of coronary artery disease: a systematic review and meta-analysis.

Brugada phenocopy: new terminology and proposed classification.

Patients with tombstoning pattern on the admission electrocardiography who have undergone primary percutaneous coronary intervention for anterior wall ST-elevation myocardial infarction: in-hospital and midterm clinical outcomes.

Natural history of early repolarization in the inferior leads.

Development and validation of a prognostic index for risk stratification of patients with early repolarization.

Electrocardiographic abnormalities in centenarians and octogenarians: a case-matched study.

Predictive value of heart rate recovery after exercise testing in addition to brain natriuretic peptide levels in ambulatory patients with nonischemic dilated cardiomyopathy.

A family with recurrent sudden death and no clinical clue.

Elimination of fatal arrhythmias through ablation of triggering premature ventricular contraction in type 3 long QT syndrome.

Incidentally found situs inversus with dextrocardia: inferior myocardial infarction in an 86-year-old woman.

Complete absence of precordial R waves due to absence of left-sided pericardium.

Bidirectional ventricular tachycardia due to coronary allograft vasculopathy a unique presentation.

Year: 2012 Volume: 17 Issue: 3

Year: 2012 Volume: 17 Issue: 2

Year: 2012 Volume: 17 Issue: 1

Year: 2011 Volume: 16

Year: 2010 Volume: 15

Year: 2009 Volume: 14

Year: 2008 Volume: 13

Development and validation of a prognostic index for risk stratification of patients with early repolarization.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Stavrakis, Stavros Patel, Nishit Te, Charles Golwala, Harsh George, Augustine Lozano, Pedro Lazzara, Ralph
Description	Country affiliation: United States Author Affiliation: Stavrakis S ( Department of Medicine Cardiovascular Section Heart Rhythm Institute, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA. stavros-stavrakis@ouhsc.edu)
Abstract	BACKGROUND: Early repolarization (ER) is associated with increased mortality in the general population. We sought to develop and validate a prognostic index (PI) of mortality in patients with ER. METHODS: We identified 852 consecutive patients (mean age 49 ± 12 years) with ER (J-point elevation ≥0.1 mV in inferior or lateral leads), from the VA electronic electrocardiogram (ECG) database. A random sample of age-matched patients with normal ECG was used as control (n = 257). The initial cohort was randomly split into a derivation and a validation cohort (2/3 and 1/3 of patients, respectively). A PI was derived from the weighed sum of the regression coefficients of each independent risk factor in the final model using Cox regression analysis. RESULTS: During a median follow-up of 6.4 years, 170 patients died. ER was associated with increased mortality compared to control (HR 1.49, 95% CI 1.05-2.12; P = 0.03). Older age, lower body mass index, non-African American race, current use of angiotensin-converting enzyme inhibitors/angiotensin receptor blockers or sulfonyureas, prolonged corrected QT (QTc), and higher ER amplitude independently predicted all-cause mortality. Annualized mortality rates were 1.3%, 2.2%, and 3.7% in the low, intermediate, and high-risk groups, respectively, in the derivation cohort (log rank P < 0.0001) and 0.8%, 1.9%, and 4.1% in the low, intermediate, and high-risk groups, respectively, in the validation cohort (log rank P < 0.0001). Model discrimination was very good (c-statistic = 0.85 and 0.80 for derivation and validation cohort, respectively). CONCLUSIONS: A PI derived from simple clinical and ECG characteristics predicts mortality in patients with ER and may be used clinically for risk stratification.
File Format	HTM / HTML
ISSN	1082720X
Issue Number	4
Volume Number	17
e-ISSN	1542474X
Journal	Annals of Noninvasive Electrocardiology
Language	English
Publisher	Wiley
Publisher Date	2012-10-01
Publisher Place	United States
Access Restriction	Subscribed
Subject Keyword	Discipline Cardiology Arrhythmias, Cardiac Diagnosis Electrocardiography Statistics & Numerical Data Heart Rate Physiopathology Cohort Studies Methods Female Humans Male Middle Aged Prognosis Reproducibility Of Results Risk Assessment Risk Factors Journal Article Validation Studies
Content Type	Text
Resource Type	Article
Subject	Physiology (medical) Cardiology and Cardiovascular Medicine

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in