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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Savalgi, Pavan B. Patgiri, Biswajyoti Thakkar, Jalaram H. Ravishankar, B. Gupta, Varun B. |
| Description | Country affiliation: India Author Affiliation: Savalgi PB ( Reader, Department of Rasa Shastra and Bhaishajya Kalpana, Ashwini Ayurvedic Medical College and Research Centre, Tumkur, Karnataka, India.) |
| Abstract | Extremely diminutive published information is available on the mutagenic activity of Ayurvedic Bhasmas. Genotoxicity of few Bhasmas were reported on single maximum dose, but no reference is available on the sub-chronic level. Hence the present study was carried to generate and evaluate genotoxic potentials of Swarna Makshika Bhasma (mineral preparation) administered at therapeutic dose for 14 days. Chromosomal aberrations and abnormal sperm assay parameters were taken in this study. Cyclophosphamide (CP) was taken as positive group and results were compared. The results revealed a lack of generation of structural deformity in above parameters by tested drugs compared to CP treated group. Observed data indicate that the Bhasmas tested were non-genotoxic under the experimental conditions. |
| File Format | HTM / HTML |
| ISSN | 09748520 |
| e-ISSN | 09769382 |
| DOI | 10.4103/0974-8520.108858 |
| Journal | AYU (An International Quarterly Journal of Research in Ayurveda) |
| Issue Number | 3 |
| Volume Number | 33 |
| Language | English |
| Publisher | Medknow Publications |
| Publisher Date | 2012-07-01 |
| Publisher Place | India |
| Access Restriction | Open |
| Subject Keyword | Discipline Naturopathy |
| Content Type | Text |
| Resource Type | Article |
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