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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Yoon, Jang W. Lee, Gi-Jong Lee, So-Young Park, Chul Yoo, Jong-Hyun Park, Hee-Myung |
| Description | Author Affiliation: Yoon JW ( Advanced Human Resource and Research Group for Medical Science (BK21), Konkuk University School of Medicine, Seoul 143-701, Korea.) |
| Abstract | A total of 74 Staphylococcus pseudintermedius strains were isolated from the 99 clinical cases of canine pyoderma or chronic otitis in our veterinary teaching hospital during May 2006-February 2008. In this study, we examined the genetic distribution of staphylococcal pyogenic toxins such as staphylococcal enterotoxins A (sea), B (seb), C (sec), D (sed), E (see), and toxic shock syndrome toxin 1 (tst) as well as the previously characterized S. intermedius exfoliative toxin (siet) among those isolates. The polymerase chain reaction analyses with the toxin gene-specific primers revealed that 18 (24.3%) of 74 S. pseudintermedius isolates carried the sec genes, but none of the sea, seb, sed, see and tst genes. Further DNA sequencing analysis of the amplified sec genes revealed that they all belonged to the canine type C staphylococcal enterotoxin (SEC(canine) ) whose superantigenic activity has been demonstrated. In addition to the sec(canine) genes, our polymerase chain reaction results showed that all the 74 isolates carried the siet gene. Since both SEC(canine) and SIET toxins are known to be biologically active, it would be interesting to investigate how those toxins are involved in the pathogenesis of the canine diseases by S. pseudintermedius such as pyoderma or chronic otitis. |
| File Format | HTM / HTML |
| ISSN | 09594493 |
| Issue Number | 5 |
| Volume Number | 21 |
| e-ISSN | 13653164 |
| Journal | Veterinary Dermatology |
| Language | English |
| Publisher | Wiley-Blackwell |
| Publisher Date | 2010-10-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Veterinary Medicine Discipline Dermatology Bacterial Toxins Metabolism Enterotoxins Exfoliatins Staphylococcus Genetics Superantigens Animals Base Sequence Dogs Gene Expression Regulation, Bacterial Physiology Molecular Sequence Data Otitis Microbiology Veterinary Prevalence Pyoderma Staphylococcal Skin Infections Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Veterinary |
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