NDLI: Medication wrong route administration: a poisons center-based study.

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Medication wrong route administration: a poisons center-based study.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Bloch-Teitelbaum, Alexandra Lüde, Saskia Rauber-Lüthy, Christine Kupferschmidt, Hugo Russmann, Stefan Kullak-Ublick, Gerd A. Ceschi, Alessandro
Spatial Coverage	Switzerland
Description	Country affiliation: Switzerland Author Affiliation: Bloch-Teitelbaum A ( Associated Institute of the University of Zurich, Swiss Toxicological Information Centre, Zurich, Switzerland.)
Abstract	OBJECTIVES: To describe clinical effects, circumstances of occurrence, management and outcomes of cases of inadvertent administration of medications by an incorrect parenteral route. METHODS: Retrospective single-center consecutive review of parenteral route errors of medications, reported to our center between January 2006 and June 2010. We collected demographic data and information on medications, route and time of administration, severity of symptoms/signs, treatment, and outcome. RESULTS: Seventy-eight cases (68 adults, 10 children) were available for analysis. The following wrong administration routes were recorded: paravenous (51%), intravenous (33%), subcutaneous (8%), and others (8%). Medications most frequently involved were iodinated x-ray contrast media (11%) and iron infusions (9%). Twenty-eight percent of the patients were asymptomatic and 54% showed mild symptoms; moderate and severe symptoms were observed in 9% and 7.7%, respectively, and were mostly due to intravenous administration errors. There was no fatal outcome. In most symptomatic cases local nonspecific treatment was performed. CONCLUSIONS: Enquiries concerning administration of medicines by an incorrect parenteral route were rare, and mainly involved iodinated x-ray contrast media and iron infusions. Most events occurred in adults and showed a benign clinical course. Although the majority of exposures concerned the paravenous route, the occasional severe cases were observed mainly after inadvertent intravenous administration.
File Format	HTM / HTML
ISSN	14740338
Issue Number	2
Volume Number	12
e-ISSN	1744764X
Journal	Expert Opinion on Drug Safety
Language	English
Publisher	Taylor & Francis
Publisher Date	2013-03-01
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Pharmacology Contrast Media Administration & Dosage Iron Medication Errors Prevention & Control Poison Control Centers Adult Aged Aged, 80 And Over Child Adverse Effects Female Humans Infant, Newborn Infusions, Intravenous Infusions, Parenteral Injections, Intravenous Injections, Subcutaneous Male Trends Middle Aged Retrospective Studies Switzerland Epidemiology Young Adult Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Pharmacology (medical)

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