NDLI: The effects of mechanical ventilation on hepato-splanchnic perfusion.

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The effects of mechanical ventilation on hepato-splanchnic perfusion.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Jakob, Stephan M.
Description	Country affiliation: Switzerland Author Affiliation: Jakob SM ( Department of Intensive Care Medicine, Bern University Hospital and University of Bern (Inselspital), Bern, Switzerland. stephan.jakob@insel.ch)
Abstract	PURPOSE OF REVIEW: Mechanical ventilation is a cornerstone of ICU treatment. Because of its interaction with blood flow and intra-abdominal pressure, mechanical ventilation has the potential to alter hepato-splanchnic perfusion, abdominal organ function and thereby outcome of the most critically ill patients. RECENT FINDINGS: Mechanical ventilation can alter hepato-splanchnic perfusion, but the effects are minimal (with moderate inspiratory pressures, tidal volumes, and positive end-expiratory pressure levels) or variable (with high ones). Routine nursing procedures may cause repeated episodes of inadequate hepato-splanchnic perfusion in critically ill patients, but an association between perfusion and multiple organ dysfunction cannot yet be determined. Clinical research continues to be challenging as a result of difficulties in measuring hepato-splanchnic blood flow at the bedside. SUMMARY: Mechanical ventilation and attempts to improve oxygenation such as intratracheal suctioning and recruitment maneuvers, may have harmful consequences in patients with already limited cardiovascular reserves or deteriorated intestinal perfusion. Due to difficulties in assessing hepato-splanchnic perfusion, such effects are often not detected.
File Format	HTM / HTML
ISSN	10705295
Issue Number	2
Volume Number	16
e-ISSN	15317072
Journal	Current Opinion in Critical Care
Language	English
Publisher	Lippincott Williams & Wilkins
Publisher Date	2010-04-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Critical Care Liver Blood Supply Perfusion Positive-pressure Respiration Respiration, Artificial Adverse Effects Splanchnic Circulation Humans Respiratory Distress Syndrome, Adult Tidal Volume Journal Article
Content Type	Text
Resource Type	Article
Subject	Critical Care and Intensive Care Medicine

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