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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Yildiz, U. Hakan Inci, Fatih Wang, ShuQi Toy, Mehlika Tekin, H. Cumhur Javaid, Asad Lau, Daryl T-Y Demirci, Utkan |
| Description | Country affiliation: United States Author Affiliation: Yildiz UH ( Demirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Stanford University School of Medicine, Canary Center at Stanford for Cancer Early Detection, Palo Alto, CA 94304, United States.); Inci F ( Demirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Stanford University School of Medicine, Canary Center at Stanford for Cancer Early Detection, Palo Alto, CA 94304, United States.); Wang S ( Demirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Stanford University School of Medicine, Canary Center at Stanford for Cancer Early Detection, Palo Alto, CA 94304, United States.); Toy M ( Department of Surgery, Stanford School of Medicine, Palo Alto, CA, United States.); Tekin HC ( Demirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Stanford University School of Medicine, Canary Center at Stanford for Cancer Early Detection, Palo Alto, CA 94304, United States.); Javaid A ( Department of Medicine, Beth Israel Deaconnes Medical Center, Harvard Medical School, Boston, MA, United States.); Lau DT ( Department of Medicine, Beth Israel Deaconnes Medical Center, Harvard Medical School, Boston, MA, United States.); Demirci U ( Demirci Bio-Acoustic-MEMS in Medicine (BAMM) Laboratory, Stanford University School of Medicine, Canary Center at Stanford for Cancer Early Detection, Palo Alto, CA 94304, United States. Electronic address: utkan@stanford.edu.) |
| Abstract | The control of hepatitis B virus (HBV) infection is a challenging task, specifically in developing countries there is limited access to diagnostics and antiviral treatment mainly due to high costs and insufficient healthcare infrastructure. Although the current diagnostic technologies can reliably detect HBV, they are relatively laborious, impractical and require expensive resources that are not suitable for resource-limited settings. Advances in micro/nanotechnology are pioneering the development of new generation methodologies in diagnosis and screening of HBV. Owing to combination of nanomaterials (metal/inorganic nanoparticles, carbon nanotubes, etc.) with microfabrication technologies, utilization of miniaturized sensors detecting HBV and other viruses from ultra-low volume of blood, serum and plasma is realized. The state-of-the-art microfluidic devices with integrated nanotechnologies potentially allow for inexpensive HBV screening at low cost. This review aims to highlight recent advances in nanotechnology and microfabrication processes that are employed for developing point-of-care (POC) HBV assays. |
| File Format | HTM / HTML |
| ISSN | 07349750 |
| e-ISSN | 18731899 |
| DOI | 10.1016/j.biotechadv.2014.11.003 |
| Journal | Biotechnology Advances |
| Issue Number | 1 |
| Volume Number | 33 |
| Language | English |
| Publisher | Elsevier |
| Publisher Date | 2015-01-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | Open |
| Subject Keyword | Discipline Biotechnology Hepatitis B Therapy Microtechnology Nanotechnology Biocompatible Materials Chemistry Diagnosis Hepatitis B Virus Growth & Development Isolation & Purification Lab-on-a-chip Devices Public Health |
| Content Type | Text |
| Resource Type | Article |
| Subject | Bioengineering Applied Microbiology and Biotechnology Biotechnology |
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