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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Jung, Ui-Won Song, Kun-Young Kim, Chang-Sung Lee, Yong-Keun Cho, Kyoo-Sung Kim, Chong-Kwan Choi, Seong-Ho |
| Description | Author Affiliation: Jung UW ( Department of Periodontology, Research Institute for Periodontal Regeneration, College of Dentistry, Yonsei University, 134 Shinchon-Dong, Seodaemun-gu, Seoul 120-752l, Korea.) |
| Abstract | The purpose of this study was to evaluate the effects of a chitosan membrane coated with polylactic and polyglycolic acid (PLGA) on bone regeneration in a rat calvarial defect. Surgical implantation of chitosan membranes resulted in enhanced local bone formation at both 2 and 8 weeks. In conclusion, the chitosan membrane coated with PLGA had a significant potential to induce bone formation in the rat calvarial defect model. Within the selected PLGA dose range and observation intervals, there appeared to be no meaningful differences in bone formation. |
| File Format | HTM / HTML |
| ISSN | 17486041 |
| e-ISSN | 1748605X |
| Journal | Biomedical Materials |
| Issue Number | 3 |
| Volume Number | 2 |
| Language | English |
| Publisher | IOP Publishing |
| Publisher Date | 2007-09-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | Open |
| Subject Keyword | Discipline Biomedical Engineering Bone Regeneration Physiology Bone Substitutes Therapeutic Use Chitosan Lactic Acid Polyglycolic Acid Polymers Skull Fractures Pathology Surgery Animals Chemistry Coated Materials, Biocompatible Materials Testing Membranes, Artificial Polyesters Rats, Sprague-dawley Skull Injuries Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Chemistry Business and International Management Mechanics of Materials Biomaterials Bioengineering Biomedical Engineering |
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