NDLI: Setting the stage: host invasion by HIV.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Hladik, Florian McElrath, M. Juliana
Description	Country affiliation: United States Author Affiliation: Hladik F ( Vaccine and Infectious Disease Institute, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.)
Abstract	For more than two decades, HIV has infected millions of people worldwide each year through mucosal transmission. Our knowledge of how HIV secures a foothold at both the molecular and cellular levels has been expanded by recent investigations that have applied new technologies and used improved techniques to isolate ex vivo human tissue and generate in vitro cellular models, as well as more relevant in vivo animal challenge systems. Here, we review the current concepts of the immediate events that follow viral exposure at genital mucosal sites where most documented transmissions occur. Furthermore, we discuss the gaps in our knowledge that are relevant to future studies, which will shape strategies for effective HIV prevention.
File Format	HTM / HTML
ISSN	14741733
e-ISSN	14741741
DOI	10.1038/nri2302
Journal	Nature Reviews Immunology
Issue Number	6
Volume Number	8
Language	English
Publisher	Nature Publishing Group
Publisher Date	2008-06-01
Publisher Place	Great Britain (UK)
Access Restriction	Open
Subject Keyword	Discipline Immunology Hiv Infections Immunology Transmission Hiv-1 Pathogenicity Animals Prevention & Control Virology Comparative Study Research Support, N.i.h., Extramural Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Immunology and Allergy Immunology

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
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Critical issues in mucosal immunity for HIV-1 vaccine development.

Multiple independent lineages of HIV-1 persist in breast milk and plasma.

The mouth: a gateway or a trap for HIV?

Acute HIV-1 Infection.

Foreskin surface area and HIV acquisition in Rakai, Uganda (size matters).

Mucosal immunology of the genital and gastrointestinal tracts and HIV-1 infection.

Epidemiologically linked transmission of HIV-1 illustrates the impact of host genetics on virological outcome.

Unravelling the mechanisms of durable control of HIV-1.

Domestic violence and prevention of mother-to-child transmission of HIV-1.

Setting the stage: host invasion by HIV.

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