NDLI: Vascular lesions in pigs experimentally infected with porcine circovirus type 2 serogroup B.

Please wait, while we are loading the content...

Year: 2017 Volume: 54

Year: 2017

Year: 2016 Volume: 53

Year: 2016

Year: 2015 Volume: 52

Year: 2014 Volume: 51

Year: 2013 Volume: 50

Year: 2012 Volume: 49

Year: 2011 Volume: 48

Year: 2010 Volume: 47

Year: 2010 Volume: 47 Issue: 6

Year: 2010 Volume: 47 Issue: 5

Year: 2010 Volume: 47 Issue: 4

Year: 2010 Volume: 47 Issue: 3

Year: 2010 Volume: 47 Issue: 2

Year: 2010 Volume: 47 Issue: 1

A European perspective.

Veterinary pathology in Japan.

Special focus on emerging diseases and global surveillance.

Emerging diseases: the global express.

Agricultural diseases on the move early in the third millennium.

Global climate change and implications for disease emergence.

Emergence of diseases from wildlife reservoirs.

Monitoring and investigating natural disease by veterinary pathologists in diagnostic laboratories.

Food and pharmaceuticals. Lessons learned from global contaminations with melamine/cyanuric acid and diethylene glycol.

Emerging and reemerging influenza virus infections.

Preclinical models of restenosis and their application in the evaluation of drug-eluting stent systems.

Growth factors as active participants in carcinogenesis: a perspective.

RAD51 protein expression is increased in canine mammary carcinomas.

Congenital hepatic fibrosis in 5 dogs.

Zygomycotic lymphadenitis in slaughtered feedlot cattle.

Adenomatous polyp with intestinal metaplasia of the esophagus (Barrett esophagus) in a dog.

Situs inversus in Dpcd/Poll-/-, Nme7-/- , and Pkd1l1-/- mice.

A rhabdomyoma within a multilocular thymic cyst in a p53-null mouse.

Spontaneous basal cell carcinoma in a 7-week-old Sprague-Dawley rat.

Vascular lesions in pigs experimentally infected with porcine circovirus type 2 serogroup B.

Lung tumor development and spontaneous regression in lambs coinfected with Jaagsiekte sheep retrovirus and ovine lentivirus.

Peliosis hepatis in cats is not associated with Bartonella henselae infections.

Molecular basis for hair loss in mice carrying a novel nonsense mutation (Hrrh-R ) in the hairless gene (Hr).

Severe histiolymphocytic and heterophilic bronchopneumonia as a reaction to in ovo fowlpox vaccination in broiler chicks.

Urinary bladder mass in a dog.

Primary site of sea lion carcinomas.

Year: 2009 Volume: 46

Year: 2008 Volume: 45

Year: 2006 Volume: 43

Vascular lesions in pigs experimentally infected with porcine circovirus type 2 serogroup B.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Langohr, I. M. Stevenson, G. W. Nelson, E. A. Lenz, S. D. HogenEsch, H. Wei, H. Pogranichniy, R. M.
Description	Country affiliation: United States Author Affiliation: Langohr IM ( Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA. langohri@dcpah.msu.edu)
Abstract	Vasculitis is a hallmark lesion of the severe form of systemic porcine circovirus-associated disease (PCVAD). In 2 experimental studies with porcine circovirus type 2 serogroup b (PCV2b), 2 pigs developed fatal PCVAD with acute vasculitis, and 5 related pigs developed chronic lymphohistiocytic and plasmacytic peri- and endarteritis. Five of these pigs (1 with acute vasculitis and 4 with chronic vasculitis) had also been inoculated with bovine viral diarrhea virus type 1 (BVDV1) or BVDV1-like virus. Vascular lesions were similar, independent of whether pigs had been inoculated singly with PCV2b or dually with PCV2b and BVDV1 or BVDV1-like virus. The acute vasculitis was accompanied by marked pulmonary and mesenteric edema and pleural effusion. In situ hybridization demonstrated abundant intracytoplasmic porcine circovirus type 2 (PCV2) nucleic acid in endothelial, smooth muscle-like, and inflammatory cells within and around affected arteries. The pigs with lymphohistiocytic and plasmacytic vasculitis had lesions of systemic PCVAD, including multisystemic lymphoplasmacytic and histiocytic or granulomatous inflammation. PCV2 nucleic acid was detected in renal tubule epithelial cells, mononuclear inflammatory cells, and rare endothelial cells in noninflamed vessels in multiple tissues of these animals. The 2 pigs with acute vasculitis had no PCV2-specific antibodies (or a low titer of), whereas the pigs with lymphohistiocytic and plasmacytic vasculitis developed high antibody titers against this virus. These observations suggest that (1) acute vasculitis observed in the current studies is directly caused by PCV2b, (2) chronic vasculitis may in part be mediated by the subsequent immune response, and (3) host factors and viral strain may both contribute to vasculitis in animals infected with PCV2b.
File Format	HTM / HTML
ISSN	03009858
Issue Number	1
Volume Number	47
e-ISSN	15442217
Journal	Veterinary Pathology
Language	English
Publisher	Sage Publication
Publisher Date	2010-01-01
Publisher Place	United States
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Veterinary Medicine Discipline Pathology Circoviridae Infections Veterinary Circovirus Swine Diseases Virology Vasculitis Animals Antibodies, Viral Immunology Arteries Pathology Genetics Dna, Viral Lung Polymerase Chain Reaction Swine Journal Article Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Veterinary

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in

Evidence of shedding of porcine circovirus type 2 in milk from experimentally infected sows.

Viral distribution and lesions in Kunming mice experimentally infected with porcine circovirus type 2b.

Experimental co-infection of pigs with Bovine viral diarrhea virus 1 and Porcine circovirus-2.

Sensitive detection of Porcine circovirus-2 by droplet digital polymerase chain reaction.

First report of porcine circovirus type 2 infections in Cuba.

Detection of porcine circovirus type 2 and viral replication by in situ hybridization in primary lymphoid organs from naturally and experimentally infected pigs.

Origin of porcine circovirus type 2 (PCV2) from swine affected by PCV2-associated diseases in Croatia.

Simultaneous detection of porcine circovirus type 2, classical swine fever virus, porcine parvovirus and porcine reproductive and respiratory syndrome virus in pigs by multiplex polymerase chain reaction.

Characterization of vascular lesions in pigs affected by porcine circovirus type 2-systemic disease.

Vascular lesions in pigs experimentally infected with porcine circovirus type 2 serogroup B.

Similar Documents

Evidence of shedding of porcine circovirus type 2 in milk from experimentally infected sows.

Viral distribution and lesions in Kunming mice experimentally infected with porcine circovirus type 2b.

Experimental co-infection of pigs with Bovine viral diarrhea virus 1 and Porcine circovirus-2.

Sensitive detection of Porcine circovirus-2 by droplet digital polymerase chain reaction.

First report of porcine circovirus type 2 infections in Cuba.

Detection of porcine circovirus type 2 and viral replication by in situ hybridization in primary lymphoid organs from naturally and experimentally infected pigs.

Origin of porcine circovirus type 2 (PCV2) from swine affected by PCV2-associated diseases in Croatia.

Simultaneous detection of porcine circovirus type 2, classical swine fever virus, porcine parvovirus and porcine reproductive and respiratory syndrome virus in pigs by multiplex polymerase chain reaction.

Characterization of vascular lesions in pigs affected by porcine circovirus type 2-systemic disease.

Vascular lesions in pigs experimentally infected with porcine circovirus type 2 serogroup B.