NDLI: Differences among international pharyngitis guidelines: not just academic.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Matthys, Jan De Meyere, Marc Van Driel, Mieke L. De Sutter, An
Spatial Coverage	Europe North America
Description	Country affiliation: Belgium Author Affiliation: Matthys J ( Department of Family Medicine and Primary Health Care, Ghent University, Belgium. jan.matthys@ugent.be)
Abstract	PURPOSE: Many countries have national guidelines for the treatment of pharyngitis. We wanted to compare the recommendations and the reported evidence in national guidelines for the management of acute sore throat in adults. METHODS: Guidelines were retrieved via MEDLINE and EMBASE and through a Web-based search for guideline development organizations. The content of the recommendations and the underlying evidence were analyzed with qualitative and bibliometric methods. RESULTS: We included 4 North American and 6 European guidelines. Recommendations differ with regard to the use of a rapid antigen test and throat culture and with the indication for antibiotics. The North American, French, and Finnish guidelines consider diagnosis of group A streptococcus essential, and prevention of acute rheumatic fever remains an important reason to prescribe antibiotics. In 4 of the 6 European guidelines, acute sore throat is considered a self-limiting disease and antibiotics are not recommended. The evidence used to underpin these guidelines was different in North America and Europe. North American guidelines cited more North American references than did European guidelines (87.2% vs 48.0%; ods ratio, 4.6-11.9; P<.001). CONCLUSION: Although the evidence for the management of acute sore throat is easily available, national guidelines are different with regard to the choice of evidence and the interpretation for clinical practice. Also a transparent and standardized guideline development method is lacking. These findings are important in the context of appropriate antibiotic use, the problem of growing antimicrobial resistance, and costs for the community.
File Format	HTM / HTML
ISSN	15441709
e-ISSN	15441717
Journal	The Annals of Family Medicine
Issue Number	5
Volume Number	5
Language	English
Publisher	Annals of Family Medicine Inc
Publisher Date	2007-09-01
Publisher Place	United States
Access Restriction	Open
Subject Keyword	Discipline Family Medicine Cross-cultural Comparison Pharyngitis Diagnosis Therapy Practice Guidelines As Topic Anti-bacterial Agents Therapeutic Use Evidence-based Medicine North America Penicillins Etiology Streptococcal Infections Complications Comparative Study
Content Type	Text
Resource Type	Article
Subject	Family Practice

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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