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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Petrochelli Banzato, Thais Godinho, Antonio Francisco da Silva Zacarin, Elaine Cristina Mathias Perobelli, Juliana Elaine Dal Bianco Fernandez, Carla Favareto, Ana Paula Alves De Grava Kempinas, Wilma |
| Description | Country affiliation: Brazil Author Affiliation: Petrochelli Banzato T ( Graduate Program in General and Applied Biology , Institute of Biosciences, UNESP-Univ Estadual Paulista, Botucatu, SP, Brazil.) |
| Abstract | Recent studies indicate that several anomalies of the male reproductive system may be produced by acute or chronic exposure to chemical substances released into the environment, attributed to increased industrial development. Among these substances are trace metals such as cadmium (Cd). The aim of this study was to assess reproductive parameters in adult male rats whose mothers were exposed to Cd during pregnancy and lactation. For this, pregnant rats were divided into two experimental groups: treated rats, which received ad libitum cadmium acetate (CdAc) solution in distilled water (10 mg Cd/L), and control rats, which received sodium acetate (NaAc) solution in distilled water (equimolar to the CdAc). The results showed that the exposure to Cd in utero and through lactation adversely affected sperm quality of adult rats, as evidenced by compromised sperm morphology and motility and increased rate of cell death in testis. |
| File Format | HTM / HTML |
| ISSN | 15287394 |
| Issue Number | 16-17 |
| Volume Number | 75 |
| e-ISSN | 10872620 |
| Journal | Journal of Toxicology and Environmental Health, Part A |
| Language | English |
| Publisher | Taylor & Francis |
| Publisher Date | 2012-01-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | One Nation One Subscription (ONOS) |
| Subject Keyword | Discipline Environmental Health Discipline Toxicology Cadmium Toxicity Lactation Prenatal Exposure Delayed Effects Semen Analysis Spermatozoa Drug Effects Animals Administration & Dosage Female Male Pregnancy Random Allocation Rats Rats, Wistar Testis Pathology Journal Article Research Support, Non-u.s. Gov't |
| Content Type | Text |
| Resource Type | Article |
| Subject | Health, Toxicology and Mutagenesis Toxicology |
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