NDLI: Short-term effect of dark chocolate consumption on routine haemostasis testing.

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Short-term effect of dark chocolate consumption on routine haemostasis testing.

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Short-term effect of dark chocolate consumption on routine haemostasis testing.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Montagnana, Martina Danese, Elisa Salvagno, Gian Luca Lippi, Giuseppe
Description	Country affiliation: Italy Author Affiliation: Montagnana M ( a Section of Clinical Biochemistry , University of Verona , Verona , Italy.); Danese E ( a Section of Clinical Biochemistry , University of Verona , Verona , Italy.); Salvagno GL ( a Section of Clinical Biochemistry , University of Verona , Verona , Italy.); Lippi G ( a Section of Clinical Biochemistry , University of Verona , Verona , Italy.)
Abstract	This experimental study was designed to investigate the sort-term impact of dark chocolate ingestion on routine haemostasis tests in healthy volunteers. The study population consisted in 15 healthy male volunteers who ingested 50 g of 90% cocoa chocolate within 3-5 min. Blood was drawn early in the morning, immediately before chocolate ingestion and 4 h afterwards, for assessment of activated partial thromboplastin time (APTT), prothrombin time (PT) and fibrinogen. A significant increase of triglycerides (1.4 ± 0.6 versus 1.0 ± 0.5 mmol/L; p < .001), APTT (32.1 ± 2.2 versus 31.1 ± 2.0 s; p < .001) and PT (9.8 ± 0.5 versus 9.7 ± 0.4 s; p = .008) was observed 4 h after ingestion of dark chocolate, whereas fibrinogen values remained unchanged (2.6 ± 0.5 versus 2.5 ± 0.5 g/L; p = .063). Overall, we observed a mean percentage increase of 3.1% for APTT and 1.2% for PT. These results suggest that dark chocolate intake may have an impact on secondary haemostasis.
File Format	HTM / HTML
ISSN	09637486
Journal	International Journal of Food Sciences and Nutrition
e-ISSN	14653478
Language	English
Publisher	Taylor & Francis
Publisher Date	2016-12-14
Publisher Place	Great Britain (UK)
Access Restriction	One Nation One Subscription (ONOS)
Subject Keyword	Discipline Nutritional Sciences
Content Type	Text
Resource Type	Article
Subject	Food Science

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