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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Schrey, Aaron W. Alvarez, Mariano Foust, Christy M. Kilvitis, Holly J. Lee, Jacob D. Liebl, Andrea L. Martin, Lynn B. Richards, Christina L. Robertson, Marta |
| Description | Country affiliation: United States Author Affiliation: Schrey AW ( Department of Biology, Armstrong Atlantic State University, 11935 Abercorn Street, Savannah, GA 31419, USA. aaron.schrey@armstrong.edu) |
| Abstract | Ecological Epigenetics studies the relationship between epigenetic variation and ecologically relevant phenotypic variation. As molecular epigenetic mechanisms often control gene expression, even across generations, they may impact many evolutionary processes. Multiple molecular epigenetic mechanisms exist, but methylation of DNA so far has dominated the Ecological Epigenetic literature. There are several molecular techniques used to screen methylation of DNA; here, we focus on the most common technique, methylation-sensitive-AFLP (MS-AFLP), which is used to identify genome-wide methylation patterns. We review studies that used MS-AFLP to address ecological questions, that describe which taxa have been investigated, and that identify general trends in the field. We then discuss, noting the general themes, four studies across taxa that demonstrate characteristics that increase the inferences that can be made from MS-AFLP data; we suggest that future MS-AFLP studies should incorporate these methods and techniques. We then review the short-comings of MS-AFLP and suggest alternative techniques that might address some of these limitations. Finally, we make specific suggestions for future research on MS-AFLP and identify questions that are most compelling and tractable in the short term. |
| File Format | HTM / HTML |
| ISSN | 15407063 |
| e-ISSN | 15577023 |
| Journal | Integrative and Comparative Biology |
| Issue Number | 2 |
| Volume Number | 53 |
| Language | English |
| Publisher | Oxford University Press |
| Publisher Date | 2013-08-01 |
| Publisher Place | Great Britain (UK) |
| Access Restriction | Open |
| Subject Keyword | Discipline Zoology Discipline Biology Amplified Fragment Length Polymorphism Analysis Dna Methylation Genetics Ecology Epigenomics Animals Biological Evolution Genetic Variation Phenotype Research Support, Non-u.s. Gov't Research Support, U.s. Gov't, Non-p.h.s. |
| Content Type | Text |
| Resource Type | Article |
| Subject | Plant Science Medicine Animal Science and Zoology |
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