NDLI: Biosafety testing of genetically modified ryegrass (Lolium perenne) using a model for the optimum selection of test invertebrates.

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Biosafety testing of genetically modified ryegrass (Lolium perenne) using a model for the optimum selection of test invertebrates.

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Biosafety testing of genetically modified ryegrass (Lolium perenne) using a model for the optimum selection of test invertebrates.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Barratt, B. I. P. Todd, J. H. Ferguson, C. M. Crook, K. Burgess, E. P. J. Barraclough, E. I. Malone, L. A.
Spatial Coverage	New Zealand
Description	Country affiliation: New Zealand Author Affiliation: Barratt BI ( AgResearch Invermay, Private Bag 50034, Mosgiel, New Zealand. barbara.barratt@agresearch.co.nz)
Abstract	Selection of test species for use in biosafety evaluation of genetically modified plants is challenging but important, as regulators in many jurisdictions require tests to determine the potential for adverse environmental impacts before the release of plants into the environment. This contribution provides an example of an evidence-based process whereby species from the receiving environment can be ranked in order of susceptibility to potential impact, and guide test species selection. The case study used for this example was ryegrass, a forage plant, which had been modified to produce elevated levels of the lipid triacylglyceride. The previously described priority ranking of nontarget invertebrates model (PRONTI), designed to rank invertebrates for biosafety testing, has been adapted for use with these plants, which could, potentially, be beneficial to invertebrate populations, and applied to data on 246 known pasture invertebrate species. The output from the model for the top 20 ranked pasture invertebrate species is discussed, the attributes of these are considered along with the level of uncertainty in the information used. Consideration is given to how the model output can be interpreted and used in a biosafety risk assessment. While some subjectivity is involved in establishing the scores, all invertebrate species are subjected to the same analysis, and treated equally. In this way, regulators have a method of a risk assessment that is evidence-based, and transparent in its assumptions thereby avoiding potential for bias.
File Format	HTM / HTML
ISSN	0046225X
e-ISSN	19382936
Journal	Environmental Entomology
Issue Number	4
Volume Number	42
Language	English
Publisher	Oxford University Press
Publisher Date	2013-08-01
Publisher Place	Great Britain (UK)
Access Restriction	Open
Subject Keyword	Discipline Zoology Invertebrates Drug Effects Lolium Toxicity Plants, Genetically Modified Triglycerides Animals Chemistry Genetics Models, Biological New Zealand Pest Control, Biological Risk Assessment Research Support, Non-u.s. Gov't
Content Type	Text
Resource Type	Article
Subject	Ecology Ecology, Evolution, Behavior and Systematics Insect Science

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Tier-1 assays for assessing the toxicity of insecticidal proteins produced by genetically engineered plants to non-target arthropods.

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Facilitation of a Native Pest of Rice, Stenotus rubrovittatus (Hemiptera: Miridae), by the Non-Native Lolium multiflorum (Cyperales: Poaceae) in an Agricultural Landscape

Divergent Selection for Seed Ability to Germinate at Extreme Temperatures in Perennial Ryegrass (Lolium perenne L.)

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Foraging activity of bumblebees (Bombus terrestris L.) on Bt-expressing eggplants

The Effect of Human Insect Repellents on Perennial Ryegrass (Lolium perenne) Growth and Recovery

Mechanism of Resistance to Glyphosate in Lolium perenne from Argentina

Biosafety testing of genetically modified ryegrass (Lolium perenne) using a model for the optimum selection of test invertebrates.

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