NDLI: Aktuelle Probleme der Nierentransplantation.

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Aktuelle Probleme der Nierentransplantation.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Haller, H. Richter, N. Bröcker, V. Gwinner, W. Gueler, F. Schwarz, A.
Description	Author Affiliation: Haller H ( Klinik für Nieren- und Hochdruckerkrankungen, Medizinische Hochschule Hannover, Hannover. haller.hermann@mh-hannover.de)
Abstract	The long-term problems after kidney transplantation have changed considerably in recent years. While formerly immunosuppression and prevention of acute rejection were of prime concern, now attention focuses on chronic alterations of the transplanted organ and long-term survival of the patients. The transplantation procedure itself has evolved into a standardized technique with a high level of surgical quality. Problems involving organ preservation and ischemia/reperfusion damage also play a role, especially in view of chronic aspects. Monitoring of long-term complications should follow a program for the transplanted organ as well as a program for the patient. Monitoring kidney function should address the organ more precisely than has previously been the case. Serum creatinine level and proteinuria alone provide insufficient information and only change long after cellular deterioration has begun. Hence it is imperative that new testing methods be developed. One possibility is offered by protocol biopsies that allow histological and molecular analysis of the kidney at regular intervals. The patient programs concentrate on diagnostics and treatment of the cardiovascular diseases. Furthermore, the patients must be screened for occurrence of neoplasia. There are no prospective studies covering all cardiovascular risk factors after kidney transplantation. This pertains particularly to the subject of hypertension.
File Format	HTM / HTML
ISSN	00209554
Issue Number	5
Journal	Der Internist
Volume Number	50
e-ISSN	14321289
Language	German
Publisher	Springer
Publisher Date	2009-05-01
Publisher Place	Germany
Access Restriction	Subscribed
Subject Keyword	Discipline Internal Medicine Graft Occlusion, Vascular Etiology Graft Rejection Kidney Transplantation Adverse Effects Trends Humans English Abstract Journal Article Review
Alternative Title	Current problems of kidney transplantation
Content Type	Text
Resource Type	Article
Subject	Internal Medicine

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