NDLI: Lebertransplantation: Indikationen und Ergebnisse.

Content Provider	World Health Organization (WHO)-Global Index Medicus
Author	Strassburg, C. P. Manns, M. P.
Description	Author Affiliation: Strassburg CP ( Klinik für Gastroenterologie, Hepatologie und Endokrinologie, Medizinische Hochschule Hannover, Hannover. Strassburg.christian@mh-hannover.de)
Abstract	After around 64,000 transplantations in Europe since 1988 liver transplantation has emerged as a standard treatment option for otherwise incurable chronic liver diseases. Cirrhosis of different etiologies represents the most frequent transplant indication. Overall survival in this group amounts to 72% after 5 years, and 62% after 10 years. In Germany, the main indications include alcoholic liver cirrhosis, tumors with increasing numbers in recent years, as well as viral diseases leading to cirrhosis. Since December 2006 the priority for liver transplantation is determined by the model for end stage liver disease (MELD) and not by the length of waiting time. MELD is a statistical model based on serum creatinine, serum bilirubin and coagulation, which describes the probability of 3-month mortality of a potential transplant candidate. Not all liver diseases are adequately represented by MELD necessitating the additional use of a defined number of standard exceptions that have been last updated in 2008. As a consequence of these developments indications, selection of recipients and the management of the waiting list have seen profound change.
File Format	HTM / HTML
ISSN	00209554
Issue Number	5
Journal	Der Internist
Volume Number	50
e-ISSN	14321289
Language	German
Publisher	Springer
Publisher Date	2009-05-01
Publisher Place	Germany
Access Restriction	Subscribed
Subject Keyword	Discipline Internal Medicine Liver Cirrhosis Surgery Liver Transplantation Methods Trends Humans Patient Selection English Abstract Journal Article Review
Alternative Title	Liver transplantation: indications and results
Content Type	Text
Resource Type	Article
Subject	Internal Medicine

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