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| Content Provider | World Health Organization (WHO)-Global Index Medicus |
|---|---|
| Author | Sauter, D. Ostermann, H. Selleng, K. Spiekermann, K. |
| Description | Author Affiliation: Sauter D ( Medizinische Klinik und Poliklinik III, Klinikum der Universität München Grosshadern, München, Deutschland. Daniela.Sauter@med.uni-muenchen.de) |
| Abstract | We report a case of a patient with thrombocytopenia. A sporadic MYH9-associated disease, May Hegglin anomaly, was identified by giant platelets, leucocyte inclusion bodies and the typical distribution of NMMHC-IIA in granulocytes in the absence of impaired renal function, cataract and hearing loss. MYH9-associated diseases are an underestimated differential diagnosis of idiopathic thrombocytopenia. The correct diagnosis is important to prevent unnecessary treatment of a patient with thrombocytopenia and to provide sufficient patient information and genetic counseling. Therefore, careful examination of the blood smear has to be the first diagnostic step in a case of unexplained thrombocytopenia. |
| File Format | HTM / HTML |
| ISSN | 00209554 |
| Issue Number | 2 |
| Volume Number | 52 |
| e-ISSN | 14321289 |
| Journal | Der Internist |
| Language | German |
| Publisher | Springer |
| Publisher Date | 2011-02-01 |
| Publisher Place | Germany |
| Access Restriction | Subscribed |
| Subject Keyword | Discipline Internal Medicine Immune Complex Diseases Complications Diagnosis Thrombocytopenia Etiology Adult Diagnosis, Differential Humans Therapy Treatment Outcome Case Reports English Abstract Journal Article |
| Alternative Title | Therapy-refractory thrombocytopenia in a 28-year-old patient |
| Content Type | Text |
| Resource Type | Case study Article |
| Subject | Internal Medicine |
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